Adoptive cell therapy using chimeric antigen receptor (CAR)-engineered T cells has emerged as a very promising approach to combating cancer. Despite its ability to eliminate tumors shown in some clinical trials, CAR-T cell therapy involves some significant safety challenges, such as cytokine release syndrome (CRS) and "on-target, off-tumor" toxicity, which is related to poor control of the dose...

We present a rare case of microgranular variant acute promyelocytic leukemia (APL) associated with ider(17)(q10)t(15;17)(q22;q12) of an old-age patient. The initial chromosome study showed a 46,XX,del(6)(?q21q25),der(15)t(15;17)(q22;q12),ider(17)(q10)t(15;17)[10]/47,sl,+ider(17)(q10)t(15;17)[3]/46,XX[16]. FISH signals from a dual color dual fusion translocation PML-RARA probe were consistent wi...

In Chen, Cook, Kao, and Zhu (2013), it is demonstrated, as a network DEA pitfall, that while the multiplier and envelopment DEA models are dual models and equivalent under the standard DEA, such is not necessarily true for the two types of network DEAmodels in deriving divisional efficiency scores and frontier projections. As a reaction to this work, we demonstrate that the duality in the stand...

We study t-structures generated by sets of objects which satisfy a condition weaker than the compactness. also weight structures cogenerated satisfying dual condition. Under some appropriate hypothesis, it turns out that structure is right adjacent to t-structure.

background: the co-existence of under and overnutrition might be influenced by a marked shift in dietary and lifestyle practices of people in developing countries. objective: this study aims to identify the factors associated with the occurrence of a dual form of malnutrition in the same households in a rural district in peninsular malaysia. methods: this study was conducted in two phases. the ...

This study examined the effect of working memory training on vocabulary recall and retention ofIranian EFL learners using dual N-back task technique. To this end, 50 EFL learners at IslamicAzad University of Shoushtar were randomly assigned to the experimental (n = 25) and control (n= 25) groups. Before the treatment, a vocabulary test was administered to the participants to assessthe participa...

In this paper, two compact quad-channel and six-channel diplexer are designed and fabricated using defected microstrip structure (DMS). This structure is designed for the desired frequency based on the literature reviews. The proposed configuration is composed of a conventional T-junction divider with two pairs of open bended stubs and dual/tri-band filters. In designing dual band filters, a lo...

Motivated by various applications to computer vision, we consider an integer convex optimization problem which is the dual of the convex cost network flow problem. In this paper, we first propose a new primal algorithm for computing an optimal solution of the problem. Our primal algorithm iteratively updates primal variables by solving associated minimum cut problems. The main contribution in t...

OBJECTIVE To evaluate the T-SPOT.TB interferon-γ releasing assay and the tuberculin skin test (TST), for the diagnosis of latent tuberculosis infection(LTBI) and the development of subsequent active tuberculosis, in BCG-vaccinated HIV-infected individuals. METHODS HIV-infected individuals without clinical suspicion of active TB or a past history of TB were enrolled from 1 January 2008 to 30 N...