s 1. Xue-Ming Xu, Jinguo Chen, Luping Wang, Xu-Fang Pei, Shanmin Yang, Charles B. Underhill and Lurong Zhang: Peptides derived endostatin and angiostatin inhibits tumor growth. Proc. Annu. Meet. Am. Assoc. Cancer Res 2002; 43:1084:5364 2. Luping Wang, Jianjin Wang, Jiyao Yu, Haoyong Ning, Xu-Fang Pei, Jinguo Chen, XueMing Xu, Shanmin Yang, Charles B. Underhill, Lei Liu and Lurong Zhang: Express...

One of the dominant trends in modern pharmacology is the creation of drugs that act directly on the lesion focus and have minimal toxicity on healthy tissues and organs. This problem is particularly acute in relation to oncologic diseases. Short tissue- and organ-specific peptides capable of delivering drugs to the affected organ or tissue are considered promising targeted agents that can be us...

Many neurodegenerative disorders (NDDs) are characterized by aggregation of aberrant proteins and extensive oxidative stress in brain cells. As a treatment option for NDDs, RNA interference (RNAi) is a promising approach to suppress the activation of abnormal genes and negative regulators of antioxidant genes. Efficient neuro-targeted siRNA delivery requires a delicate optimization of nucleic a...