background: solid targets that consist of powder and electrodeposited targets are used commonly to produce radionuclides by accelerators. since silver is easily electrodeposited in cyanide baths and has a very excellent thermal conductivity, the electrodeposited target is preferable to produce 109cd. to avoid cracking or peeling of the target during bombardment, it should have a level surface a...

In this commentary, Hamer, Hill and Harrison critically appraise a systematic review comparing lower versus standard targeted blood pressure how impacts morbidity mortality in people with hypertension.

This paper presents a modified form of the Walker-Anderson (W-A) model for analyzing high velocity penetration of an eroding projectile into a concrete target in which the W-A model is improved by incorporating calculations for the plastic flow field of concrete in terms of its compressibility and strain rate sensitivity under severe pressure. With the changes to and calculations of plastic fie...

Background: HLA-G is a nonclassical HLA class I molecule which, when elevated in tumor cells, is one of the main factors involved in tumor evasion of immune responses including NK and T cells. Objective: To evaluate the effect of HLA-G downregulation on NK cell cytotoxicity in tumor cell lines. Methods: The expression level of HLA-G was measured by real-time PCR and flowcytometry after transfec...

Protein specific aptamers are highly applicable affinity ligands in different fields of research and clinical applications. They have been developed against various targets, in particular, bio-macromolecules such as proteins. Among human proteins, the coagulation factors are the most attractive targets for aptamer selection and their specific aptamers had valuable characteristics in therapeutic...

The Hedgehog (Hh) signalling pathway is one of the key regulators of metazoan development. Hh proteins have been shown to play roles in many developmental processes and have become paradigms for classical morphogens. Dysfunction of the Hh pathway underlies a number of human developmental abnormalities and diseases, making it an important therapeutic target. Interest in Hh signalling thus extend...