Background: Accidents are the second reason for mortality and morbidity in Iran. Among them, brain injuries are the most important damage. Clarification of the effects of brain injuries on different body systems will help physicians to prioritize their treatment strategies. In this study, the effect of pure brain trauma on the cardiovascular system and lungs 24 hours post trauma was assessed. M...

Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality in young adults and children, and is a leading public health problem worldwide. In TBI, neurological impairment is caused by immediate brain tissue disruption (primary injury) and post‑injury cellular and molecular events (secondary injury) that exacerbate the primary neurological insult. However, the destructi...

Traumatic brain injury (TBI) is physical damage to the brain structure which has a high global rate of mortality and morbidity. TBI can cause intense inflammatory response due to accumulation of leukocytes in cerebral matrix and activation of microglia. Microglia can differentiate into M1 macrophages or M2 macrophages following the changes in biochemical properties of brain tissue. M1 sub type ...

objectives the aim of this study was to present the incidence and characteristics of repeated tbi (rtbi) in iranian patients. patients and methods during one year, all admitted tbi patients with prior tbi history were enrolled into the study. in each patient, data such as age, gender, past medical history, injury cause, anatomic site of injury, tbi severity, clinical findings and ct scan findin...

traumatic brain injury (tbi) is an important clinical problem in the worldwide and especially due to breaking driving rules in iran, but undesirable consequences of trauma can persist for the rest of patient’s life. we investigated the effect of a novel weight drop model of tbi on incidence of seizure 2 weeks after tbi. in this regard, 21 male wistar rat weighted 250-300 gr randomly were divide...

background traumatic brain injury (tbi) is a worldwide problem, especially in countries with high incidences of road traffic accidents such as iran. patients with a single occurrence of tbi have been shown to be at increased risk to future tbi. this study presents incidences and characteristics of repeated traumatic brain injury (rtbi) in iran. materials and methods during one year, all admitte...

It is unknown whether the severity, timing, and quality of graft-versus-host disease (GVHD) may be different after nonmyeloablative as compared with myeloablative hematopoietic stem cell transplantation (HSCT). Therefore, GVHD incidence, morbidity of skin, liver, and gut, requirements for immunosuppressive therapy, and survival were retrospectively analyzed in 44 patients who underwent nonablat...