Therapeutic drug monitoring (TDM) of carbamazepine (CBZ) in saliva is an attractive alternative, because its collection is painless, non-invasive and simpler than drawing blood. Salivary drug levels, also closely reflect the free drug concentration. The aim of the study was to evaluate the suitability of saliva in routine TDM of CBZ in adult epileptic patients. Blood and saliva samples were tak...

This article is based on a study that analyzed the impacts of employer-based transportation demand management (TDM) strategies and the performance of a transportation system. The study simulated the effects of the Washington State Commute Trip Reduction (CTR) programs implemented by 189 employers on an 8.6-mile segment of I-5 in the Seattle downtown area. This comprehensive dataset included bef...

Introduction and aim: Therapeutic drug monitoring (TDM) of vancomycin aims to achieve an optimal response minimize the risk toxicity by keeping plasma levels within therapeutic range. In this study, we aimed evaluate treatment appropriateness TDM in patients receiving vancomycin. 
 Method: For purpose, who received ICUs a university hospital during 8-month period between January August 202...

In this paper we have proposed a next generation hybrid WDM/TDM based PON architecture. We have analyzed the role of WDM in access networks, the challenges and strategies to enable smooth and economical migration from current TDM-PONs to future WDM-PONs. The proposed architecture is based on collector ring and distributed star networks that can support both existing TDMPONs and new WDM-PONs. Th...

MMSE-FDE can improve the transmission performance of OFDM combined with time division multiplexing (OFDM/TDM), but knowledge of the channel state information and the noise variance is required to compute the MMSE weight. In this paper, a performance evaluation of OFDM/TDM using MMSE-FDE with pilot-assisted channel estimation over a fast fading channel is presented. To improve the tracking abili...

BACKGROUND The management of uterine-serous-carcinoma (USC) no longer amenable to treatment with surgery, radiation and/or chemotherapy remains dismal. Alternative therapeutic options are desperately needed. CASE We describe the case of a heavily pretreated 74-year-old patient with a recurrent USC overexpressing HER2/neu at 3 + level by IHC treated with the anti-HER2/neu antibody-drug-conjuga...

Faculty of Electrical Engineering, Mathematics and Computer Science CE-MS-2012-05 A streaming application like software defined radio (SDR) executed on a heterogeneous multi-processor system on chip (MPSoC) consists of various transceiver jobs that have to be scheduled on different processors concurrently. The hard real time performance requirements of these jobs can be guaranteed on the multi-...

Tomographic diffractive microscopy (TDM) is a label-free imaging technique that reconstructs the 3D refractive index map of the probed object with an improved resolution compared to confocal microscopy. In this work, we consider a TDM implementation in which the sample is deposited on a reflective substrate. We show that this configuration requires calibration and inversion procedures that acco...

In this letter, we introduce frequency-domain spacetime transmit diversity (STTD) encoding/decoding to orthogonal frequency division multiplexing combined with time division multiplexing (OFDM/TDM) on a frame-by-frame basis (i.e., over several concatenated OFDM signals in the frequency-domain) to achieve both spatial and frequency diversity gains and improve the bit error rate (BER) performance...