OBJECTIVE Area 7 of the autonomous region of Madrid has one of the highest incidences of tuberculosis (23/100,000 population per year 2004). This study aimed to identify tuberculosis control in this area. METHODS A descriptive study of tuberculosis cases diagnosed in area 7 from January 1, 1999 to December 31, 2004 was carried out by analyzing the incidence of tuberculosis and the management ...

In clinical research, questionnaires are an important tool available for population and large family studies to gather information on a patient’s medical history. In 1989, we described a large kindred of FrenchCanadian descent with an 8-fold increased risk of venous thrombosis due to the 3363C insertion in the protein C gene [1]. We developed a questionnaire for use in this family to assess gen...

A new score statistic is derived, which uses information from registries (age-specific incidences) and family studies (sib-sib marginal correlation) to weight affected sibling pairs according to their age at onset. Age at onset of sibling pairs is modelled by a gamma frailty model. From this model we derive a bivariate survival function, which depends on the marginal survival and on the margina...

We conducted a tuberculosis contact investigation for a female military recruit with an unreported history of multidrug-resistant tuberculosis (MDRTB) and subsequent recurrence. Pertinent issues included identification of likely contacts from separate training phases, uncertainty on latent MDRTB infection treatment regimens and side effects, and subsequent dispersal of the contacts after exposure.

Invariantism proposed by [Braun, 2013] aims to maintain full identity of semantic content between all uses of ‘might’. I invoke well-known facts regarding diachronic change in meanings of modals to argue that invariantism commits us to implausible duplication of familiar processes of lexical semantic change on the level of “lexical pragmatics”, with no obvious payoff. [Braun, 2013] proposes an ...

The content of the audit and vulnerability testing information telecommunication system (ITS) any enterprise is considered. Based on results security audit, overall company's ITS assessed. It proposed to assess IT using penetration in following areas: from outside inside infrastructure, social engineering personnel for resistance DDoS attacks; assessment mobile application, web resource wireles...