A facile and efficient molecularly imprinted polymer (MIP) recognition element of electrochemical sensor was fabricated by directly electro-polymerizing monomer o-phenylenediamine (oPD) in the presence of template quinoxaline-2-carboxylic acid (QCA), based on one-step controllable electrochemical modification of poly(pyrrole)-graphene oxide-binuclear phthalocyanine cobalt (II) sulphonate (PPY-G...

The replication of the hepatitis C viral (HCV) genome is accomplished by the NS5B RNA-dependent RNA polymerase (RdRp), for which mechanistic understanding and structure-guided drug design efforts have been hampered by its propensity to crystallize in a closed, polymerization-incompetent state. The removal of an autoinhibitory β-hairpin loop from genotype 2a HCV NS5B increases de novo RNA synthe...

Zirconium oxide (ZrO2) has generated wide interest because of its potential in applications such as solid oxide fuel cells, catalysts and optical devices. In these applications, it is important to control the grain size of the material and increase the surface area by introducing porosity with tailored pore size. This paper presents a synthesis route for the preparation of mesoporous zirconia u...

In this paper, we report on the simple, reliable synthesis of polypyrrole (PPy)/graphene oxide (GO) composite nanosheets by using sacrificial-template polymerization method. Herein, MnO(2) nanoslices were chosen as a sacrificial-template to deposit PPy, which served as the oxidant as well. During the polymerization of pyrrole on surface of GO nanosheets, MnO(2) component was consumed incessantl...

The repair of DNA double-strand breaks (DSBs) requires open, flexible chromatin domains. The NuA4-Tip60 complex creates these flexible chromatin structures by exchanging histone H2A.Z onto nucleosomes and promoting acetylation of histone H4. Here, we demonstrate that the accumulation of H2A.Z on nucleosomes at DSBs is transient, and that rapid eviction of H2A.Z is required for DSB repair. Anp32...

Early detection and removal of pulmonary nodules significantly improves long term survival rates for patients with lung cancer. This paper provides the overview of different methods used in the retrieval system of lung nodules by a comprehensive review of existing literature. Firstly, the high level features of DICOM CT images are used for retrieval of filtered lung images from the database. Th...

Harrison, P.G. and H. Khoshnevisan, A new approach to recursion removal, Theoretical Computer Science 93 (1992) 91-113. Iterative forms are derived for a class of recursive functions, i.e. the recursion is “removed”. The transformation comprises first analysis of the defining equation of a recursive function and then synthesis of an imperative language loop from the primitive subexpressions so ...

This paper presents an implementation of a system designed for location of human faces and facial features such as pupils, eyes, nose and mouth. The kernel of the system is an integration of several algorithms, such as human face center -of-gravity template, illumination compensation, and so on . A false-face removal algorithm is proposed in this paper especially for the distinguish ing of cart...

A major challenge that arises when growing GaN substrates in a single run process is the remaining curvature of the freestanding material after the removal of the foreign substrate. For a long time the dislocation density gradient has been suspected to be the cause. However, by conducting etching experiments, we have found that this cannot be the only reason. We postulate that the initial strai...

Phosphonoacetic acid specifically inhibited human cytomegalovirus DNA synthesis in virus-infected human fibroblasts as detected by virus-specific nucleic acid hybridization. Inhibition was reversible; viral DNA synthesis resumed upon the removal of the drug. The compound partially inhibited DNA synthesis of host cells in the log phase of growth but had little effect on confluent cells. Studies ...