BACKGROUND Stroke survivors may not be receiving optimal rehabilitation as a result of a shortage of hospital resources, and many of them are institutionalized. A rehabilitation program provided in a short-term residential care setting may help to fill the service gap. OBJECTIVES The primary objectives of this study were, first, to examine whether there were significant differences in terms o...

the equivalent noise level in large cities has been growing due to the population growth, uncontrolled production of cars, and the existence of worn out cars. on the other hand, heavy traffic has increased the amount of noise problems for residents of medical and educational centers, research institutes and residential area (or sensitive centers to noise) built in highway bounds and it has also...

cAMP induces a protein-synthesis-dependent late phase of long-term potentiation (LTP) at CA3-CA1 synapses in acute hippocampal slices. Herein we report cAMP-mediated LTP and long-term depression (LTD) at monosynaptic CA3-CA1 cell pairs in organotypic hippocampal slice cultures. After bath application of the membrane-permeable cAMP analog adenosine 3',5'-cyclic monophosphorothioate, Sp isomer (S...

A WHO methodology is used for the first time to estimate the burden of disease directly associated with incomplete water and sanitation provision in refugee camps in sub-Saharan African countries. In refugee camps of seven countries, containing just fewer than 1 million people in 2005, there were 132,000 cases of diarrhoea and over 280,000 reported cases of malaria attributable to incomplete wa...

To examine signaling mechanisms relevant to cAMP/protein kinase A (PKA)-dependent endothelial cell barrier regulation, we investigated the impact of the cAMP/PKA inhibitors Rp diastereomer of adenosine 3',5'-cyclic monophosphorothioate (Rp-cAMPS) and PKA inhibitor (PKI) on bovine pulmonary artery and bovine lung microvascular endothelial cell cytoskeleton reorganization. Rp-cAMPS as well as PKI...

Recent studies demonstrate a role for cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) in the nucleus accumbens (NAc) in reward-related learning. To clarify this role, we assessed the effect of PKA inhibition on the unconditioned and conditioned locomotor activating properties of intra-NAc amphetamine. Rats underwent three 60 min conditioning sessions, pairing a test environ...

BACKGROUND Few epidemiological studies of air pollution have used residential histories to develop long-term retrospective exposure estimates for multiple ambient air pollutants and vehicle and industrial emissions. We present such an exposure assessment for a Canadian population-based lung cancer case-control study of 8353 individuals using self-reported residential histories from 1975 to 1994...

Rooted in the near repeat phenomenon and police crime analysis, a crime “flare up” or micro-time hot spot is the emergence of several closely-related crimes within a few minutes’ travel distance from one another. It occurs within 1–2 weeks and can last several weeks or months before running its course and cooling down. A micro-time hot spot is a type of crime pattern identified by police crime ...

In this paper, I propose the platform business model to transform classical Hospital using new digital technologies. The ecosystem framework is developed for healthcare service sector where all stake holders including core health providers (Hospitals, Pharma manufacturers), Complementors (Diagnostic labs, Pharmacies, Startups), Homecare providers, Software Social media, R&D Medical schools, Yog...