Tetraploid (4N) cells are considered important in cancer because they can display increased tumorigenicity, resistance to conventional therapies, and are believed to be precursors to whole chromosome aneuploidy. It is therefore important to determine how tetraploid cancer cells arise, and how to target them. P53 is a tumor suppressor protein and key regulator of tetraploidy. As part of the "tet...

Phenotypic plasticity is one of the main mechanisms adaptation to abiotic stresses via changes in critical developmental stages. Altering flowering phenology a key evolutionary strategy plant stresses, achieve maximum possible reproduction. The current study first apply linear regression residuals as drought scores while considering variation and traits under non-stress conditions. We character...