Currently, precision theranostics have been extensively demanded for the effective treatment of various human diseases. Currently, efficient therapy at the targeted disease areas still remains challenging since most available drug molecules lack of selectivity to the pathological sites. Among different approaches, light-mediated therapeutic strategy has recently emerged as a promising and power...

A commercially available rapid fluorescent in situ hybridization (FISH) test, (seaFAST H. pylori Combi-Kit; SeaPro Theranostics International, Lelystad, The Netherlands) was used to simultaneously detect the presence of Helicobacter pylori and determine clarithromycin susceptibility in paraffin-embedded biopsy sections. The FISH method was found to be 97% sensitive, 94% specific for the detecti...

This commentary highlights the findings by Kessinger et al. (Theranostics 2011; 1: 263-275) that dynamic T(2)*-weighted magnetic resonance imaging (MRI) of cyclic RGD peptide-encoded superparamagnetic polymeric micelle (SPPM) nanoparticles allows quantitative analysis of tumor integrin αvβ3 expression, which can exclude the effect of blood volume and extravascular signal components and thus pro...

Gallium-68 a positron emitter radionuclide, with great impact on the nuclear medicine, has been widely used in positron emission tomography (PET) diagnosis of various malignancies in humans during more recent years especially in neuroendocrine tumors (NETs). The vast number of 68Ge/68Ga related generator productions, targeting molecule design (proteins, antibody fragments,...

Nanomedicine helps to fight diseases at the cellular and molecular level by utilizing unique properties of quasi-atomic particles at a size scale ranging from 1 to 100 nm. Nanoparticles are used in therapeutic and diagnostic approaches, referred to as theranostics. The aim of this review is to illustrate the application of general principles of nanotechnology to select examples of life sciences...

Institute of Computational Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany Chair of Mathematical Modeling of Biological Systems, Center for Mathematics, Technische Universität München, 85748 Garching, Germany Alacris Theranostics GmbH, 12489 Berlin, Germany Max Planck Institute for Molecular Genetics, 14195 Berlin, Germany Dahlem Centre for Genome Research and Medical Systems Biol...

Health care modalities that are more predictable and effective the result of advances in early diagnosis precise treatment options. Aptamers three-dimensional structures made nucleic acids selectively bind to a target site. In creation aptamer-based drug delivery systems, physicochemical properties aptamers, their conjugation with nanoparticles (NPs) theranostics, internalization have been foun...

• The synthesis and modification methods of different types 2D nanomaterials are reviewed. Recent advances in for cancer treatment imaging systematically summarized. nanomaterial-based theranostics comprehensively outlook challenges biomedical applications discussed. Two-dimensional (2D) have drawn much attention by virtue their unique physicochemical properties numerous potential applications....