نتایج جستجو برای: therapeutic failure

تعداد نتایج: 703127  

Journal: :gastroenterology and hepatology from bed to bench 0
parichehr hassanzadeh pharmd, phd

obesity with an increasing prevalence rate worldwide is correlated with multiple comorbidities. unfortunately, the currently available therapies such as the pharmacotherapy, bariatric surgery or gene-transfer technology are associated with a number of disadvantages including undesirable side effects, poor compliance or transient effectiveness. therefore, modifications of the lifestyle factors m...

Journal: :iranian journal of pharmaceutical sciences 0
hashem montaseria department of pharmaceutics hasan merrikhi department of toxicology and pharmacology, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran mohammad javad khoshnoud assistance professor, department of toxicology and pharmacology, faculty of pharmacy, shiraz university of medical sciences, shiraz, iran bita geramizadeh department of pathology, faculty of medicine, shiraz university of medical sciences, shiraz, iran

sirolimus is a potent immunosuppressive agent administered as prophylactic agent to prevent rejection after organ transplantation. sirolimus must be used within a narrow therapeutic window. due to inter- and intra-variability, sirolimus blood concentrations may be affected, therefore, there is no possibility of predicting the sirolimus blood concentrations based on the dose patients received. t...

Fariba Jaffary, Hadis Tahmasebi Poor, Latifeh Abdellahi, Mohammad Ali Nilforoushzadeh,

Background: Despite advances in diagnosis and treatment, leishmaniasis is now considered a severe public health problem, particularly in developing countries, such as Iran. Leishmaniasis is among the six most important, parasitic diseases of the world affecting 88 countries in almost every continent. The disease is complex with different clinical presentations such as visceral, cutaneous and mu...

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