Minimally invasive stereotactic tumor ablation is a viable option for the treatment of benign and malignant intracranial lesions. Although surgical excision constitutes first-line therapy for various brain pathologies, it can cause irreversible neurologic deficits. Additionally, many patients who may benefit from surgery do not qualify as surgical candidates due to multiple comorbidities. Recen...

Knowledge of the distributions of temperature in cardiac tissue during and after ablation is important in advancing a basic understanding of this process, and for improving its efficacy in treating arrhythmias. Technologies that enable real-time temperature detection and thermal characterization in the transmural direction can help to predict the depths and sizes of lesion that form. Herein, ma...

Physical mechanisms of UV-laser ablation of polyimide (Kapton H) are discussed for different laser pulse duration from long (p,s) to ultra-short (ps) laser pulses. Theoretical analysis of experimental data suggests that with long laser pulses the mechanism appears to be thermal. The activation energies for ablation are about 1.5 eV, and typical temperatures lie in the range 1400-1800 K. With ns...

Cryoablation has been used for many years during open surgery and is an effective method of tissue destruction. The ice ball may be easier than the RFA cloud to monitor with ultrasound, and cryo may be more effective in the ablation of tumor touching large blood vessels (speculative). However, RFA has less inflammatory response, less blood loss, fewer complications, and is easier to perform per...

OBJECTIVES Although the clinical benefits of endovenous thermal ablation are widely recognized, few studies have evaluated the health economic implications of different treatments. This study compares 6-month clinical outcomes and cost-effectiveness of endovenous laser ablation (EVLA) compared with radiofrequency ablation (RFA) in the setting of a randomized clinical trial. METHODS Patients w...

Despite numerous studies, the mechanistic understanding of the role of the photochemical processes and their coupling with the thermal processes in UV laser ablation is still far from being complete. In this work, the effects of the photochemical reactions on the laser ablation mechanism are delineated based on the results of molecular dynamics simulations of 248 nm laser irradiation of solid c...

Tumor ablation is a minimally invasive technique used to deliver chemical, thermal, electrical, or ultrasonic damage to a specific focal tumor in an attempt to achieve substantial tumor destruction or complete eradication. As the technology continues to advance, several image-guided tumor ablations have emerged to effectively manage primary and secondary malignancies in the liver. Percutaneous ...

The therapies for hepatocellular carcinomas (HCCs) have remarkably developed during the recent one or two decades and the prognosis of HCC patients has subsequently much improved. At present we have been able to perform several therapeutic modalities for HCC, such as surgical resection, transplantation, loco-regional therapies including percutaneous ethanol injection (PEI), radiofrequency ablat...