BACKGROUND There is conflicting evidence as to whether Alzheimer disease (AD) is accompanied by loss of retinal ganglion cells. To evaluate this issue, we have used optical coherence tomography (OCT) to assess the thickness and volume of the retina. We have also sought to correlate our findings with visual function and cognitive impairment. METHODS We evaluated 28 eyes of 14 patients with AD ...

PURPOSE In the chick, compensation for experimentally induced defocus involves changes in the thickness of the choroid. The choroid thickens in response to imposed myopic defocus and thins in response to imposed hyperopic defocus. This study was undertaken to determine whether similar choroidal changes occur in the primate eye with induced refractive errors. METHODS Thirty-three common marmos...

AIM To investigate the effect of pregnancy on subfoveal choroidal thickness (SFCT) and macular thickness in both pregnant and not pregnant healthy women. METHODS Twenty-nine healthy pregnant women in their third trimester and 36 age-matched healthy women were enrolled in a prospective, cross-sectional study. Foveal and parafoveal thickness in the four quadrants and SFCT were measured by optic...

AIM To assess the role of three-dimensional endoanal ultrasound (3D-EAUS) for morphological assessment of the anal sphincter of female patients with chronic proctalgia (CP). METHODS In this unmatched case control study, 30 consecutive female patients with CP and 25 normal women (control group) were enrolled. 3D-EAUS was performed in all subjects. Thickness and length of internal anal sphincte...

introduction: in the present research, the effect of morphine consumption during pregnancy on the development of the embryo’s spinal cord was studied in wistar rat. methods: female wistar rats (wt: 250-300 g) were mated with males. the test group received morphine (0.01 mg/ml) in their drinking water. pregnant rats were later killed with chloroform on the 12th, 13th and 14th days of pregnancy, ...

PURPOSE To compare the effect of conventional and femtosecond laser-assisted (Alcon LenSx Inc) phacoemulsification on the macula using optical coherence tomography (OCT). METHODS Twenty eyes of 20 patients underwent uneventful cataract surgery in both study groups: femtosecond laser-assisted (laser group) and conventional phacoemulsification (control group). Macular thickness and volume were ...

Measurements of central cornea thickness (CCT) have a very important value in glaucoma patients; if the central cornea is thinner than it suggests, then the intraocular pressure is falsely low. This study compares the central cornea thickness between patients with pseudoexfoliative glaucoma, open angle glaucoma, angle closure glaucoma and control group. This study included 34 patients with pseu...

A fence post design, when viewed on a plot of index of refraction versus film thickness, has thin (usually of equal thickness) high-index posts that stand above a broad low-index ground. Monitoring fence post and related posthole designs offers error compensation and error reduction. There tend to be two or more extrema within the optical monitoring trace of each layer between the fence posts t...

Results: The mean (SD) ages of the patients with PD and healthy subjects were 64.0(6.5) years vs 63.5(10.7) years (P=.77). The mean (SD) intraocular pressure was 13.6 ( /−2.7) mm Hg in the PD patients. No difference was found in either the superior or inferior outer retinal layer thickness of PD vs control eyes. The mean (SD) superior inner retinal layer thickness of PD vs control eyes was 88.7...