OBJECTIVE • To prospectively evaluate the risk of positive surgical margins and local recurrence after blunt tumour enucleation (TE) with no ablation of the tumour bed. PATIENTS AND METHODS • Between 2005 and 2007, data were gathered prospectively from 201 consecutive patients who had open TE with no ablation of the tumour bed. • Overall, 164 consecutive patients had TE for single sporadic re...

Depth-averaged thin-layer models are commonly used to model rapid gravity-driven flows such as debris or avalanches. However, the formal derivation of equations for general topographies is not straightforward. The curvature topography results in a force that maintains velocity tangent topography. Another term appears bottom friction with frictional rheologies. In this work, we present main line...

Meandering instability is familiar to everyone through river meandering or small rivulets of rain flowing down a windshield. However, its physical understanding is still premature, although it could inspire researchers in various fields, such as nonlinear science, fluid mechanics and geophysics, to resolve their long-standing problems. Here, we perform a small-scale experiment in which air flow...

BACKGROUND We developed a silicon-based biosensor that generates visual, qualitative results or quantitative results for the detection of protein or nucleic acid targets in a multiplex format. METHODS Capture probes were immobilized either passively or covalently on the optically coated surface of the biosensor. Intermolecular interactions of the immobilized capture probe with specific target...

Primary wound contact layer dressings play a vital part in wound management, as they both absorb light volumes of wound fluid and help to remove excess exudate (Wound Union of Wound Healing Societies [WUWHS], 2007), hence protecting the wound bed. They tend to be used in the early stages of healing to promote the growth of granulation and epithelial tissue (Benbow, 2002). As they are thin, non-...

A uniform array of single-grain Au nanodots, as small as 5-8 nm, can be formed on silicon using e-beam lithography. The as-fabricated nanodots are amorphous, and thermal annealing converts them to pure Au single crystals covered with a thin SiO(2) layer. These findings are based on physical measurements, such as atomic force microscopy (AFM), atomic-resolution scanning transmission electron mic...

In this communication, we show the feasibility of the pulsed laser ablation technique to make very thin, uniform luminescent coatings on particulate systems. To deposit continuous particulate coatings, the laser-induced plume from the target comes in contact with an agitated bed of core particles ~size 1 mm!. The pressure and nature of the background gas ~inert or active! controls the cluster s...

“He was indeed a deplorable spectacle. In the dim light of a foggy November day the sick room was a gloomy spot, but it was that gaunt, wasted face staring at me from the bed which sent a chill to my heart. His eyes had the brightness of fever, there was a hectic flush upon either cheek, and dark crusts clung to his lips; the thin hands upon the coverlet twitched incessantly, his voice was croa...

I was called on the evening of 14th June last to see a patient who was said to be unable to drink water on account of pain in the side. The patient was about 20 years of age, in fair health, though somewhat thin, and was lying in bed on his face. His pulse was almost imperceptible and his limbs cold. On attempting to bring a light near him he was terrified, and could not bear it. He shouted not...