Acute leukaemia is the most common form of childhood cancer and is the primary cause of cancer-related mortality in children. The major initiating event in infant leukaemia is rearrangement of the Mil gene at 1 lq23, and such leukaemias have a poor survival rate. Chromosomal translocations occur commonly in leukaemia and an in-frame fusion gene is created with altered properties to the original...

Munc13-1 functions as an essential synaptic vesicle priming factor (Brose et al., 2000). Vesicle fusion, on the Abteilung Membranbiophysik Am Faßberg 11 other hand, is thought to be mediated by the concerted action of the synaptic vesicle protein Synaptobrevin/ D-37077 Gö ttingen Bundesrepublik Deutschland VAMP (vesicle associated membrane protein) and the two synaptic plasma membrane proteins ...

The effect of divalent cations on cell fusion by concentrated Sendai virus, inactivated by beta-propiolactone, was investigated using Vero and mouse L-929 cells in monolayers. With both cell lines, which are normally resistant to exogenous viral fusion, Cu(2+) in sublethal concentrations was found to promote polykaryon formation to a marked degree. The simultaneous presence of Cu(2+) and virus ...

The experience of willing an act arises from interpreting one's thought as the cause of the act. Conscious will is thus experienced as a function of the priority, consistency, and exclusivity of the thought about the action. The thought must occur before the action, be consistent with the action, and not be accompanied by other causes. An experiment illustrating the role of priority found that ...

This paper proposes a novel Subdivision-Fusion Model (SFM) to recognize human actions. In most action recognition tasks, overlapping feature distribution is a common problem leading to overfitting. In the subdivision stage of the proposed SFM, samples in each category are clustered. Then, such samples are grouped into multiple more concentrated subcategories. Boundaries for the subcategories ar...