Integrins play crucial roles in cell adhesion, migration, and signaling by providing transmembrane links between the extracellular matrix and the cytoskeleton. Integrins cluster in macromolecular complexes to generate cell-matrix adhesions such as focal adhesions. In this mini-review, we compare certain integrin-based biological responses and signaling during cell interactions with standard 2D ...

Three-dimensional (3D) printing technology has revolutionized tissue engineering field because of its excellent potential of accurately positioning cell-laden constructs. One of the main challenges in the formation of functional engineered tissues is the lack of an efficient and extensive network of microvessels to support cell viability. By printing vascular cells and appropriate biomaterials,...

Three-dimensional (3D) culture models represent a better approximation of solid tumor tissue architecture, especially cell adhesion, in vivo than two-dimensional (2D) cultures do. Here, we explored the role of architecture in chemosensitivity to platinum in colon cancer. Under the 3D culture condition, colon cancer cells formed multicellular spheroids, consisting of layers of cells. 3D cultures...

This study was conducted to compare the heat shock responses of cells grown in 2D and 3D culture environments as indicated by the level of heat shock protein 70 expression and the incidence of apoptosis and necrosis of prostate cancer cell lines in response to graded hyperthermia. PC3 cells were stably transduced with a dual reporter system composed of two tandem expression cassettes-a conditio...

Abstract Many studies have shown, using two‐dimensional culture, that low‐temperature plasma‐jet‐activated medium (PAM) inhibits the growth of various tumor cells, whereas its effects and mechanisms in three‐dimensional (3D) culture system remain unclear. In this study, a 3D cell model was used to study inhibition tumorigenesis PAM vitro. Our results showed significantly suppressed spheroid for...

In the paper, it makes 3-D (three dimensional) printing rapid prototyping bitmap data compression research based on bytes has been conducted, in the 3-D printing rapid prototyping system, where the bitmap data format is adopted, and related data storage space is very large. It firstly analyzes the bitmap data characteristics in 3-D printing rapid prototyping system and the commonly methods used...

Cholangiocarcinoma (CCA) is a lethal malignancy which occurs with relatively high incidence in Thailand. This cancer is often difficult to diagnose and associated with high mortality. The secretome, containing the secreted proteins from cells, are potentially useful as biomarkers of cancers. Since three-dimensional (3D) cell culture may mimic growth characteristics and microenvironment of solid...

We propose differential holography as a method to overcome the long-standing forward-scattering problem in photoelectron holography and related techniques for the three-dimensional imaging of atoms. Atomic images reconstructed from experimental and theoretical Cu 3p holograms from Cu(001) demonstrate that this method suppresses strong forward-scattering effects so as to yield more accurate thre...

Mailing address: Marcelo Luiz Campos Vieira • Rua Cardoso de Melo, 463/21 04548-002 São Paulo, SP Brazil E-mail: [email protected] Manuscript received January 09, 2007; revised manuscript received January 01, 2007; accepted March 13, 2007. The use of three-dimensional echocardiography for the analysis of cardiac structures allows the viewing of planes that make the anatomic identification m...