Novel Approaches in Cancer Study Analysis of Thrombosis Risk Stratification Models Based on 10 Years Follow up 237 Essential Thrombocythemia Patients Adam Kellner1, Vasana Peter Rajnics1, Eva Karádi1, Arpad Illes2, Miklos Udvardy2, Lajos Homor3, Dombi4, Jozsef Herczeg1, Zoltan Sipiczki5, Viktoria Gyorine Korom1, and Egyed1 1Department Hematology, Hungary 2Department 3Faculty Humanities Social S...

jak2 is a tyrosine kinase that plays an important role in the signaling pathways of many hematopoietic growth factor receptors. a single acquired point mutation – v617f – in jak2 occurs in the great majority of patients with polycythemia vera (pv) and approximately half of the patients with idiopathic myelofibrosis (imf) or essential thrombocythemia (et). in contrast, the jak2-v617f mutation is...