nigella sativa (ns) (ranunculaceae family) is generally utilized as a therapeutic plant all over the world. the seeds of the plant have a long history of use in different frameworks of medicines and food. in islamic literature, it is considered as one of the greatest forms of therapeutics. it has been widely used to treat nervous system diseases such as memory impairment, epilepsy, neurotoxicit...

nigella sativa (n. sativa) is a spice plant which has been traditionally used for culinary and medicinal purposes. different therapeutic properties including the beneficial effects on asthma and dyspnea, digestive and gynecology disorders have been described for the seeds of n. sativa. there is evidence of the relaxant effects of this plant and some of its constituents on different types of smo...

objective(s):acrylamide (acr) has broad applications in different industries. it also forms in food during heating process. oxidative stress has a critical role in acr-induced neurotoxicity in both in vitro and in vivo models; therefore, the aim of the current study was the evaluation of effects of thymoquinone, the main constituent of volatile oil from nigella sativa seeds in acr-induced neuro...

Nigella sativa (N. sativa) grows in various parts of the world, particularly in Iran. It has been traditionally used as a folk remedy to treat a number of diseases. The seeds of this plant contain moisture, proteins, carbohydrates, crude fiber, alkaloids, saponins, ash, fixed oils and essential oil. The major components of the essential oil are thymoquinone, p-cymene, trans-anethole, 2-methyl-5...

Objectives: Previous studies have shown the role of oxidative stress in methanol (MeOH) neurotoxicity. In clinical practice ethanol (EtOH) was used for treatment MeOH intoxication. Treatment with EtOH results depression central nervous system, which may occur even at therapeutic doses. It also induces stress. Antioxidant and neuroprotective effects thymoquinone (TQ) are known different models T...

Abstract Background Phytochemicals and plant extracts are showing promising anticancer potentials. In the current study, volatile faction (essential oil) of Nigella sativa seeds was evaluated against some hepatocellular carcinoma (HCC). The essential oil extracted characterized by chromatographic techniques to reveal its chemical composition, especially thymoquinone. Then, fabricated in two nan...