n page 1163, Gerhardt et al. present a mechanism to explain the function of VEGF in angiogenesis. Their findings implicate a specialized cell at the tips of vessels in guiding the growth of new sprouts, with cell mass provided by the division of different cells that lie further back. The authors examined angiogenesis in mice retina. Retinal O Tip cell (green) filopodia follow VEGF-A–expressing ...

n page 1163, Gerhardt et al. present a mechanism to explain the function of VEGF in angiogenesis. Their findings implicate a specialized cell at the tips of vessels in guiding the growth of new sprouts, with cell mass provided by the division of different cells that lie further back. The authors examined angiogenesis in mice retina. Retinal O Tip cell (green) filopodia follow VEGF-A–expressing ...

AIM Surgical anatomy concerning the posterior craniovertebral region in fresh human cadavers was studied to provide most accurate information for the surgical approach. MATERIAL AND METHODS In thirty-two fresh human cadavers, the distance from the posterior tubercle to the sulcus of vertebral artery (VA), the thickness and length of the third segment of VA (V3), the distance of C1/C2 facet to...

OBJECTIVE The management of nonmalignant pain by morphine pump implantation has become an effective and increasingly frequent strategy of care. We report a rare complication of intrathecal granuloma formation adjacent to the intrathecal catheter tip resulting in spinal cord compression in four patients undergoing intrathecal treatment for chronic pain. METHODS Four patients presented with chr...

Nomenclature L y spanwise coordinate q net beam loading S shear M bending moment θ deflection angle (= dw/dx) w deflection κ local beam curvature ′ lift/span distribution ′ S η normalized spanwise coordinate (= 2y/b) c local wing chord wing wing area b wing span λ taper ratio E Young's modulus δ tip deflection N load factor m wing mass/span distribution I bending inertia i spanwise station inde...

We use archival Spitzer Space Telescope photometry of the old, super-solar metallicity massive open cluster NGC6791 to look for evidence of enhanced mass loss, which has been postulated to explain the optical luminosity function and low white dwarf masses in this benchmark cluster. We find a conspicuous lack of evidence for prolificacy of circumstellar dust production that would have been expec...

To perform remote and direct sampling for mass spectrometry, solid probe assisted nanoelectrospray ionization (SPA-nanoESI) has been newly developed. After capturing the sample on the tip of the needle by sticking it to the biological tissue, the needle was inserted into the solvent-preloaded nanoESI capillary from the backside. NanoESI gave abundant ion signals for human kidney tissues and the...

A mass with a diameter of 0.8 cm was detected in the aortic root of a 53 year old woman during routine preoperative cross sectional echocardiographic assessment of a secundum atrial septal defect. Intraoperative epicardial echocardiography showed that the mass was attached by a slender stalk to the tip of the left coronary cusp of the aortic valve, and histological examination showed that it wa...

(Chest 1991; 100:1444-46) A 71-year-old white male farmer presented with a five-week history of a mass on his left mandible. He had a 70 pack-year smoking history. He reported a 9.1 kg (20 pound) weight loss and occasional production of blood streaked sputum. There was a nontender, freely mobile and erythematous 5 cm nodule on his left mandible (Fig 1). He also had a fixed, firm, nontender 3 cm...

The present study performs a set of static tests to demonstrate novel passive morphing concept. concept introduces bend–twist coupled composite spar rotor blades, allowing for twist be achieved by imposing lagwise bending moment using centrifugal forces produced movable mass at the blade tip. First, three spars are fabricated symmetric layup configuration with varied ply orientations. A designe...