BACKGROUND The fetal laceration is one of the most commonly identified injuries at the caesarean delivery. The incidence in the literature has been reported to be as high as 3%. The management of such injuries has remained a perplexing problem for both the physician and the parents. MATERIALS AND METHODS We present a case of a newborn who accidentally sustained laceration over the face during...

Borrelia burgdorferi is the causative agent of Lyme disease in the U.S., with at least 25,000 cases reported to the CDC each year. B. burgdorferi is thought to enter and exit the bloodstream to achieve rapid dissemination to distal tissue sites during infection. Travel through the bloodstream requires evasion of immune surveillance and pathogen clearance in the host, a process at which B. burgd...

Ocular tolerance to cyanoacrylate tissue adhesives was evaluated in rabbits. In the experimental studies, tissue adhesives were implanted intralamellarly, subconjunctivally, and in the anterior chamber. The eyes were examined clinically and histologically at different time intervals. In the cornea and conjunctiva, the adhesive reacted as any inert material. The reaction was considerably less th...

OBJECTIVE To determine the efficacy of ethyl 2-cyanoacrylate adhesive in repairing the lung parenchyma after partial lobectomy in rats, in terms of hemostasis/aerostasis, scarring, and surgical time. METHODS The study involved 30 Wistar rats, randomly divided into five groups (one control group and four study groups). In the study groups, the lung parenchyma was repaired with either cyanoacry...

Gelatin-resorcin-formalin (GRF) glue was developed by Braunwald and Tatooles in 1964. Initially, it was mainly used as a hemostatic agent by gastrointestinal surgeons and urologists. In 1977, Bachet et al. used GRF glue as an adhesive and hemostatic material for aortic surgery and reported that it was very useful. The use of GRF glue dramatically improved the outcomes of surgery for Stanford ty...

Cells adhere to each other through the binding of cell adhesion molecules at the cell surface. This process, known as cell-cell adhesion, is fundamental in many areas of biology, including early embryo development, tissue homeostasis and tumour growth. In this paper we develop a new continuous mathematical model of this phenomenon by considering the movement of cells in response to the adhesive...

Investigating cohesive tissue sheets in controlled cultures still poses a challenge since the complex intercellular interactions are difficult to mimic in in vitro models. We used supported lipid membranes functionalized by the adhesive part of the extracellular domain of the cell adhesion molecule cadherin-11 for the immobilization of pluripotent tissue sheets, the animal cap isolated from Xen...

INTRODUCTION The World Health Organization has solicited rapid and minimally invasive techniques to facilitate scale-up of voluntary medical male circumcision (VMMC). STUDY DESIGN Non-blinded randomized controlled field trial with 2:1 allocation ratio. PARTICIPANTS 75 adult male volunteers. SETTING Outpatient primary care clinic. INTERVENTION Open surgical circumcision under local anest...

A 39-year-old female visited our cardiovascular outpatient department with paresthesia and soreness around the right popliteal fossa, where thrill was palpable. There was no history of trauma, apart from her having undergone acupuncture several years previously. An arteriovenous fistula (AVF) was diagnosed by vascular ultrasonography and magnetic resonance imaging. Angiography confirmed the pre...

In a recent Letter to the Editor it was suggested that desmoplakin (DP) regulates desmosome hyper-adhesion (Hobbs and Green, 2011). The term hyper-adhesion refers to the strong, calcium-independent adhesive state adopted by desmosomes in tissues, including the epidermis (Garrod et al., 2005; Wallis et al., 2000). This contrasts with a weaker adhesive state adopted by desmosomes on initial forma...