BACKGROUND Oxidative stress in RA synovial tissue can cause DNA damage and suppress the DNA mismatch repair (MMR) system in cultured synoviocytes. This mechanism includes two enzyme complexes, hMutSalpha (hMSH2/hMSH6) and hMutSbeta (hMSH2/hMSH3). OBJECTIVE To examine the expression and distribution of MMR enzymes in synovial tissues from patients with arthritis and from normal subjects. MET...

Background/Aim. Human mammaglobin is considered to be one of the most significant markers hematogenous dissemination breast carcinoma. This paper aimed indicate important role peritumoral tissue as an active participant in tumorigenesis process and concentration/expression mammaglobins a prognostic factor. Methods. research included 64 female patients with primary carcinoma during five-year fol...