Guided tissue regeneration (GTR) is effective in halting tissue and bone destruction and promoting new tissue and bone formation. Although the goal of complete and predictable regeneration still remains elusive, many techniques and materials have been developed that show good clinical and histologic outcomes. The most commonly used materials in GTR include bone replacement grafts from numerous ...

introduction: in the present study, we hypothesized that a novel approach to promote vascularization would be to create injectable three dimensional (3-d) scaffolds within growth factor that enhance the sustained release of growth factor and induce the angiogenesis. material and methods: we demonstrate that a 3-d scaffold can be formed by mixing of peptide-amphiphile (pa) aqueous solution with ...

Wound healing refers to the body's replacement of destroyed tissue by living tissue (Walter and Israel 1987) and comprises two essential components Regeneration and Repair. The differentiation between the two is based on the resultant tissue. In regeneration, specialised tissues is replaced by the proliferation of surrounding undamaged specialised cells. In repair, lost tissue is replaced by gr...

in cartilage regeneration in the temporomandibular joint, although those are somehow effective for a variety of cells 2. Despite such promising clinical successes of GFs for tissue regeneration, controversies still hound their clinical use for tissue regeneration of the oral and maxillofacial area. The biggest debate deals with the oncogenic potential of GFs. Many tumors including malignancies ...

Digital light processing (DLP)-based bioprinting technology has been exploited for a wide range of applications in tissue repair, regeneration, disease modeling and drug screening. In article number e270, Li co-workers comprehensively summarize works about DLP-based strategy to deliver biomedical materials and/or specific cells create sophisticated structures various regeneration.

One of the major challenges in the field of regenerative medicine is how to optimize tissue regeneration in the body by therapeutically manipulating its natural ability to form scar at the time of injury or disease. It is often the balance between tissue regeneration, a process that is activated at the onset of disease, and scar formation, which develops as a result of the disease process that ...

background: the failure of regeneration after spinal cord injury (sci) has been attributed to axonal demyelination and neuronal death. cellular replacement and white matter regeneration are both necessary for sci repair. in this study, we evaluated the co-transplantation of olfactory ensheathing cells (oec) and embryonic stem (es) cell-derived motor neurons (esmn) on contused sci. methods: oec ...

objectives : stem cell (sc) therapy is a promising technique for tissue regeneration. this study aimed to compare the viability and proliferation ability of periodontal ligament stem cells (pdlscs) isolated from the periodontium of healthy and periodontitis-affected teeth to obtain an autologous, easily accessible source of scs for tissue regeneration in periodontitis patients. materials and me...

Guided tissue regeneration materials were reviewed in this paper and can be categorized as non-resorbable and bioabsorbable. Both materials have been used extensively in periodontal regeneration with no difference in the clinical outcome. Selection of barrier material depends on resorbability, size of the defect, morphology of the defect, operator preference and patient acceptance.

Present review article emphasizes role of biological scaffolds, hydrogels and stem cells in tissue engineering mainly in regeneration or repairing of damaged tissues. Highly porous scaffold biomaterials are developed which act as templates for tissue regeneration and potentially guide the growth of new tissue. Present article also describes de-cellularization, cell printing, vascularization, in...