نتایج جستجو برای: to assess heritability

تعداد نتایج: 10618307  

Journal: :Human heredity 2005
Fang-Chi Hsu Daniel J Zaccaro Leslie A Lange Donna K Arnett Carl D Langefeld Lynne E Wagenknecht David M Herrington Stephanie R Beck Barry I Freedman Donald W Bowden Stephen S Rich

OBJECTIVES Pulse pressure (PP) is a measure of large artery stiffness and has been shown to be an important predictor of cardiovascular morbidity and mortality. The aims of the present study were to investigate the heritability of PP in three studies, the Diabetes Heart Study (DHS), the Insulin Resistance Atherosclerosis Family Study (IRAS FS), and the NHLBI Family Heart Study (FHS), to estimat...

2013
Alexander Gusev Gaurav Bhatia Noah Zaitlen Bjarni J. Vilhjalmsson Dorothée Diogo Eli A. Stahl Peter K. Gregersen Jane Worthington Lars Klareskog Soumya Raychaudhuri Robert M. Plenge Bogdan Pasaniuc Alkes L. Price

Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing due to poor tagging or additional causal variants at known GWAS loci. Here, we use variance components to quantify the heritability explained by all SNPs at known GWAS loci in...

2015
Hannah Gordon Frederik Trier Moller Vibeke Andersen Marcus Harbord

Since Tysk et al's pioneering analysis of the Swedish twin registry, twin and family studies continue to support a strong genetic basis of the inflammatory bowel diseases. The coefficient of heritability for siblings of inflammatory bowel disease probands is 25 to 42 for Crohn's disease and 4 to 15 for ulcerative colitis. Heritability estimates for Crohn's disease and ulcerative colitis from po...

2001
SUBRAT KESHORI BEHERA Amrit Kumar Paul

Abstract: Heritability shows the degree of resemblance between relatives. Heritability is the most important genetic parameter on which different breeding strategy depends. The knowledge of heritability is a prerequisite for the formulation of breeding plans on scientific lines. There is need to know the heritability of different characters which are used for selection of parents for future bre...

Journal: :International Journal of Cancer 2014

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