Topiramate is a new antiepileptic drug, used for treatment of partial onset seizure and refractory seizures. Although it is well tolerated in children, some adverse effects including hypohidrosis and hyperthermia are reported. We present two children with epilepsy who were treated with topiramate and developed hypohidrosis and hyperthermia.

how to cite this article:  fallah r, akhavan karbasi s, shajari a, fromandi m. the efficacy and safety of topiramate for prophylaxis of migraine in children. iran j child neurol. 2013 autumn; 7(4):7-11. objective migraine is the most common acute intermittent primary headache in children and prophylactic therapy is indicated in children with frequent or disabling headaches. the purpose of this ...

how to cite this article: tonekaboni sh, ghazavi a, fayyazi a, khajeh a, taghdiri mm, abdollah gorji f, azargashb e. prophylaxis of childhood migraine: topiramate versus propranolol. iran j child neurol. 2013 winter; 7 (1):9-14.   objective headache is a common disabling neurological disorder and migraine comprises more than half the causes of recurrent headaches in children. despite extended p...

objective infantile spasms (is) is one of the catastrophic epileptic syndromes of infancy.the purpose of this study was to evaluate clinical efficacy and safety oftopiramate (tpm) as the first -line drug in the treatment of infantile spasms. materials and methods in a quasi- experimental study, efficacy and safety of tpm in rteatment of fortychildren with is who were referred to pediatric neuro...

Introduction The complex pharmacodynamic mechanism of topiramate is currently approved for only two major diseases: epilepsy, mono or combined therapy, and preventing episodes of migraine. However, there are many other studies that emphasize other potential clinical effects deriving from its complex action and leading to its use in acute nociceptive pain and neuropathic pain management. Topiram...