BACKGROUND Burning fat and carbohydrates to provide energy in biological systems causes the formation of free oxygen species. OBJECTIVES This study aimed to evaluate the oxidative status of serum and breast milk of mothers giving birth prematurely and at full-term. MATERIALS AND METHODS The study comprised 50 mothers who gave birth at full-term at more than 38 weeks and 43 mothers who gave ...

OBJECTIVES Our aim was to investigate mechanisms of inflammation-induced endothelial dysfunction in humans. METHODS Endothelial function in twenty-one healthy human volunteers was measured using forearm venous plethysmography before and 8 h after administration of typhoid vaccination to generate an inflammatory response. Basal and stimulated endothelial nitric oxide (NO) bioavailability was a...

BACKGROUND The aim of this study was to evaluate the changes in perioperative oxidant-antioxidant balance in ONCABG. METHODS Twenty-three patients were included in this study. Serum total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) values were assessed preoperatively, at 20 minutes after aortic clamping and at 30 minutes, 6 hours, and 48 hours after ...

Recurrent aphthous ulcer (RAU) is an inflammatory condition of the oral mucosa characterized by painful, well-circumscribed, single or multiple round or ovoid ulcerations. The exact etiologic factor(s) of these ulcerations are not yet understood. The objective of this study was to evaluate inflammatory processes and free radical metabolism of 25 patients with RAUs compared to 25 healthy control...

OBJECTIVE Disulfiram (DSF) exerts its therapeutic effects through oxidative, proteasome, and nuclear factor kappa beta (NF-κB) pathways. The study was planned to test the impact of DSF on growing of endometriotic implants in rats with experimentally induced endometriosis. PATIENTS AND METHODS Thirty rats were labeled as the control (n = 8), sham (n = 6), GnRH-agonist (n = 8) and the DSF (n = ...

Received: Revised: Accepted: November 13, 2014 February 12, 2015 February 21, 2015 Gentamicin-induced nephrotoxicity is associated with free radicals generation in kidney tissue. Medicinal plants contain bioactive constituents that act as natural antioxidants, which can protect the biological system from oxidative stress. In this study, phytochemical constituents of aqueous extract of Calotropi...

The relationship between acute and chronic exercise and expression of matrix metalloproteinases (MMPs) in muscles is unknown. There happen some alterations in the oxidant-antioxidant balance due to exercise. This study aimed to investigate the levels of MMP-1, tissue inhibitors of metalloproteinases (TIMP-1), hyaluronic acid (HA), total antioxidant status (TAS), and total oxidant status (TOS) f...

OBJECTIVE In living organisms, there is a balance between the oxidant and antioxidant systems. Reactive products continuously formed by exogenous and endogenous sources are rendered harmless by the antioxidant system. Oxidative stress is an etiological factor in aging and the development of various diseases. In the present study, the aim was to investigate the effects of meal frequency and calo...