Gamma tocopherol (gT) exhibits beneficial cardiovascular effects partly due to its anti-inflammatory activity. Important sources of gT are vegetable oils. However, little is known to what extent gT can be transferred into marine animal species such as Atlantic salmon by feeding. Therefore, in this study we have investigated the transfer of dietary gT into salmon. To this end, fish were fed a di...

In the course of our investigations of new sources of higher plant lipids, seed fatty acid compositions and the tocochromanol contents of Salvia bracteata, S. euphratica var. euphratica, S. aucherii var. canascens, S. cryptantha, S. staminea, S. limbata, S. virgata, S. hypargeia, S. halophylla, S. syriaca and S. cilicica were investigated using GLC and HPLC systems. Some of the species are ende...

Studies of dietary supplementation and cancer risk are full of surprises. Ten years ago, most epidemiologists and nutritionists sincerely believed that fl-carotene was the leading candidate for evaluation in chemoprevention trials. We now know that (3-carotene supplementation among smokers increases the risks of lung cancer, cardiovascular disease, and total mortality (1, 2). Although the story...

OBJECTIVE To examine associations of biomarkers of nutrient intake with overall diet quality. SUBJECTS A convenience sample of 102 healthy postmenopausal women in Seattle, Washington (USA). DESIGN AND METHOD Participants attended a study centre where they provided fasting blood specimens and completed a 122-item validated food-frequency questionnaire (FFQ). Data from the FFQ were used to ca...

The effect of dietary intake of marine oils (CLO and SBO) on the lipids, alpha-tocopherol and TBARS in serum and liver was investigated in rats. In the dietary fats (8% in diet), the proportion of marine oils and corn oil was changed at five steps from 100:0 to 0:100. In the groups fed more than 50% CLO, serum cholesterol levels decreased while liver cholesterol increased as compared with the r...

Data on dietary exposure to vitamin E by plasma or adipose tissue concentrations of alpha-tocopherol (alpha-T) in observational studies have failed to provide consistent support for the idea that alpha-T provides women with any protection from breast cancer. In contrast, studies indicate that alpha, gamma, and delta-tocotrienols but not alpha-T have potent anti-proliferative effects in human br...

The administration of purified ethyl Iinoleate supplemented With or without alpha-tocopherol or pyridoxal phosphate to chronically CCI4 poisoned mice proved to be effective upon recovery from the liver damage. CC14 poisoning resulted in a dramatic decrease in total lipid content of mouse liver in each diet group and administration of ethyl linoleate promoted this tendency. Gas-liquid chromatogr...

Plasma and lipoprotein alpha-tocopherol concentrations of four patients with familial isolated vitamin E deficiency and six control subjects were observed for 4 d after an oral dose (approximately 15 mg) of RRR-alpha-tocopheryl acetate labeled with six deuterium atoms (d6-tocopherol). Chylomicron d6-tocopherol concentrations were similar in the two groups. d6-Tocopherol concentrations of plasma...

In spite of their high oxidisability, long-chain n-3 PUFA protect against CVD. Dietary fatty acids modulate the fatty acid composition of lipoproteins involved in atherosclerosis. We thought that if long-chain n-3 PUFA were able to increase NO production by the aorta, then by its antioxidant activity the NO will prevent lipid peroxidation. However, the beneficial effect of NO in vivo on VLDL + ...

A simplified method for the determination of alpha-tocopherol concentration in beef muscle was developed and evaluated. The method consists of a saponification step applied to 1-g samples of intact, fresh muscle, followed by a single isooctane extraction of the saponified samples. alpha-Tocopherol in the extract was separated by normal phase chromatography and quantified by fluorescence detecti...