Although tuberculosis involves every organ and has a wide range of clinical manifestation, however involvement of the thyroid gland is rare. We report a case of a 25-yr-old female with supraclavicular lymphadenitis that developed nodular swelling of the thyroid and had symptoms and sonographic features mimicking a nodule with a cystic component. The diagnosis was made by using fine needle aspir...

Background: Suppressive therapy with levothyroxine for reducing the size of thyroid nodules has not been really accepted. The purpose of this study was to assess the effect of levothyroxine on the size of benign thyroid nodules. Methods: Forty patients with confirmed benign nodule were randomly divided into two groups. Group I received 50?g/day levothyroxin for six months but group II did not t...

Angiotensin converting enzyme was assayed in serum free culture supernatants from unstimulated rheumatoid nodule cells. Angiotensin converting enzyme was released spontaneously and the angiotensin converting enzyme derived from rheumatoid nodule cells was suppressed in a dose and time dependent manner by the protein synthesis inhibitor cycloheximide. These data suggest the constitutive de novo ...

SUPPLEMENTARY FIG. S1. (A) Schematic representation of the position of the nodule. (B) Longitudinal B-mode ultrasound (US) image showing the left inferior pole of the thyroid (white arrow) with a small (Thy2) nodule next to a symptomatic (Thy2) nodule attached to it and partly plunging (asterisk).

Sister Mary Joseph nodule or Sister Mary Joseph Sign refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. A rare case of Sister Mary Joseph nodule, manifesting as ascites, cachexia and bleeding per rectum, is presented without any primary tumor despite extensive search for the same.

PURPOSE To evaluate the effects of ultrasonography (US)-guided interstitial laser photocoagulation (ILP) on the volume of benign solitary solid cold thyroid nodules and any nodule-related symptoms. MATERIALS AND METHODS ILP was performed in 16 patients with normal thyroid function and a solid benign thyroid nodule. None of the patients had uptake on a radionuclide scan. Patients underwent one...

in 30 patient with single cold thyroid nodule and normal thyroid function tests, 99mtc-mibi scan is performed. the nodules are divided to hot (10), warm (12) and cold (8). fna reported papillary ca in 4, suspicious follicular neoplasm in 3 and 23 benign lesions. 7 patients were operated on and had final pathology reports (4 papillary ca and 3 benign lesions). all the nodules with no mibi uptake...

What is the underlying pathophysiology of thyrotoxicosis? Graves’ disease is an autoimmune disease mediated by antibodies that stimulate the thyroid stimulating hormone (TSH) receptor, leading to excess secretion of thyroid hor­ mones and hyperplasia of thyroid follicular cells, resulting in hyperthyroidism and diffuse goitre (table 1). Both genetic and environmental factors (for example, smoki...