We investigated in a rabbit model, the eye distribution of topically instilled benzalkonium_(BAK) chloride a commonly used preservative in eye drops using mass spectrometry imaging. Three groups of three New Zealand rabbits each were used: a control one without instillation, one receiving 0.01%BAK twice a day for 5 months and one with 0.2%BAK one drop a day for 1 month. After sacrifice, eyes we...

2007 Glycolysis, Respiration, and Anomalous Gene Expression in ExpérimentalHepatomas: G. H. A. Clowes Memorial Lecture. Sidney Weinhouse. 2017 Interference with Nucleoside Transport in Mouse Lymphoma Cells Proliferating in Culture. C. T. Warnick, H. Muzik, and A. R. P. Paierson. 2023 A Randomized Clinical Trial of Daunorubicin and a Combination of Prednisone, Vincristine, 6-Mercaptopurine, and...

The present study deals with isolation of different polysaccharides from Plantago Ovata husk and their use in designing the controlled release Gastro-Retentive (GR) floats of piroxicam (PRC). Gastroretentive floats are actually drug release (DR) moieties of low density used to retain the drug in stomach for maximum time to increase its bioavailability. The polysaccharides extracted from P. Ovat...

Mucilage extracted from Plantago psyllium seeds was evaluated for inertness and safety parameters. The suitability of psyllium mucilage for a pharmaceutical binder was assessed in paracetamol tablets. Properties of the granules prepared using different concentrations of psyllium mucilage was compared with PVP and tragacanth. Psyllium mucilage at 5 % (m/m) was found to be comparable with 3 % (m/...

Indian forests are a major source of large number of non-wood forest products. One such product is an exudate tree gum, regionally called as gum Kondagogu (Cochlospermum gossypium DC.), belonging to the family Bixaceae. This gum is collected by tribals in the state of Andhra Pradesh and marketed by Girijan Cooperative Society, Andhra Pradesh, India. Experimental work carried out in our laborato...

BACKGROUND In some studies, gum-chewing was demonstrated to have a beneficial effect on resumption of bowel function; however, other contradictory findings in other studies refute the effects of gum-chewing on peristaltic movements and digestive system stimulation. In addition, most previous studies were after colorectal or gynecology surgery, whereas few reports focused on the effect of gum-ch...

he reduced daily usage of nicotine gum to 16, 12, and 5 pieces, respectively, while using 3, 7, and 14 pieces of placebo gum. During week 6, he used no nicotine gum intake and averaged 17 pieces of placebo gum per day. During week 7 the 19 pieces of gum he used were divided between placebo gum and bubble gum. By week 8 and at the six-month follow-up he was using only bubble gum. We confirmed th...

We investigated brain electric field signatures of subjective feelings after chewing regular gum or gum base without flavor. 19-channel eyes-closed EEG from 20 healthy males before and after 5 minutes of chewing the two gum types in random sequence was source modeled in the frequency domain using the FFT-Dipole-Approximation. 3-dimensional brain locations and strengths (Global Field Power, GFP)...

Gum odina and various parts of the plant Odina wodier are traditionally used in Indian folk medicine. Here an effort was made to investigate the efficacy of gum odina as new pharmaceutical excipients, in particular, as an emulsifying agent. Primary emulsion was prepared using wet gum method taking oil: water: gum (4:2:1) with gum acacia powder as an emulsifying agent. This was used as a standar...