In intertemporal choice (ITC), people discount future rewards in proportion to the time delay until reward receipt. Despite recent non-invasive brain stimulation studies suggesting a general causal link between dorsolateral prefrontal cortex (dlPFC) activity and ITC impulsivity, results regarding the functional specificity of dlPFC are mixed. We used high-definition transcranial direct current ...

Transcranial direct current stimulation (tDCS) is a low-intensity, noninvasive form of brain stimulation delivered by a small battery-powered portable machine. Conventionally, 2 disposable electrodes are positioned on the head, and a small current is passed between these electrodes to stimulate the brain “transcranially.” A typical session uses a low-intensity current of 1 to 2 mA (ECT by compa...

In perceptual decision-making tasks, people balance the speed and accuracy with which they make their decisions by modulating a response threshold. Neuroimaging studies suggest that this speed-accuracy tradeoff is implemented in a corticobasal ganglia network that includes an important contribution from the pre-SMA. To test this hypothesis, we used anodal transcranial direct current stimulation...

OBJECTIVE There has been no modern effort to replicate, further characterize, or quantify the dramatic effects on affect described in controlled studies from the 1960s using bilateral frontal electrodes with an extra-cephalic reference in a mixed group composed primarily of mildly depressed individuals. We performed a comprehensive, quantitative assessment of the effects of bifrontal TDCS on em...

The opercular somatosensory region (OP) plays an indispensable role in pain perception. In the present study, we investigated the neurophysiological effects of transcranial direct current stimulation (tDCS) over the OP. Somatosensory-evoked magnetic fields following noxious intraepidermal electrical stimulation to the left index finger (pain-SEFs) were recorded before and after tDCS with a sing...

Tools for noninvasive stimulation of the brain, such as transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), have provided new insights in the study of brain-behavior relationships due to their ability to directly alter cortical activity. In particular, TMS and tDCS have proven to be useful tools for establishing causal relationships between behavioral and...

Here, we review the effects of non-invasive brain stimulation such as transcranial magnetic stimulation (TMS) or transcranial direct current stimulation (tDCS) in the rehabilitation of neglect. We found 12 studies including 172 patients (10 TMS studies and 2 tDCS studies) fulfilling our search criteria. Activity of daily living measures such as the Barthel Index or, more specifically for neglec...

Background: Transcranial Direct Current Stimulation (tDCS) of the primary motor cortex (M1) can modulate neuronal activity, and improve performance of basic motor tasks. The possibility that tDCS could assist in rehabilitation (e.g., for paresis post-stroke) offers hope but the evidence base is incomplete, with some behavioural studies reporting no effect of tDCS on complex motor learning. Olde...

Transcranial direct current stimulation (tDCS) is a technique developed more than fifty years ago [1]. tDCS acts modulating the excitability of a targeted brain area by altering neuronal membrane potentials, consequently modifying the brain circuitries related to the targeted areas [2,3]. tDCS has been recently considered as a potential non-invasive tool for neuromodulation due to its ability t...

BACKGROUND Transcranial direct current stimulation (tDCS) is an emerging non-invasive neuromodulation therapy in epilepsy with conflicting results in terms of efficacy and safety. OBJECTIVE Review the literature about the efficacy and safety of tDCS in epilepsy in humans and animals. METHODS We searched studies in PubMed, MedLine, Scopus, Web of Science and Google Scholar (January 1969 to O...