To investigate the association between immune-cell-related cytokines and development of chronic hepatitis B (CHB), patients with virus (HBV) infection in immunotolerant (IT) phase (n = 30) or envelope antigen (HBeAg)-positive CHB 250) were enrolled this study. Serological indicators plasma cytokine levels measured at time enrollment. The results showed that there significant differences median ...

Transforming growth factor betas are multifunctional polypeptides in the cytokine superfamily. They have a growth inhibitory role on hemopoietic progenitor cells in semisolid colony assay as well as in long-term bone-marrow culture. TGF - β2 represses stromal cells, stem cell factor gene transcription, and decreases the stability of c-kit transcripts in hemopoietic cells. TGF-β also modulat...