BACKGROUND Accumulation of advanced glycation end-products (AGEs) has been implicated in the pathogenesis of chronic transplant dysfunction and cardiovascular disease in renal transplant recipients. We aimed to investigate which factors are associated with tissue AGE accumulation in renal transplant recipients. METHODS The AGE accumulation was assessed using a validated skin-autofluorescence ...

conclusions in this study, the patients’ survival rate was 73%, which is quite low compared to the survival rate reported in other studies. although we only have a 12-year experience with pediatric liver transplantation, the survival rate has increased in our center through the recent years (2008-2011). however, the survival rate of the patients who had survived 3 months after the transplantati...

TOPIC: Transplantation TYPE: Fellow Case Reports INTRODUCTION: Only a few reports have detailed the discovery of non-small cell lung adenocarcinoma in explanted at time transplant (1). Herein, we present case adenocarcinoma, identified pneumonectomy specimen, determined to metastasized post-transplant period. CASE PRESENTATION: We reviewed 61-year-old Caucasian male bilateral recipient secondar...

OBJECTIVES Kidney transplant in mouse model is quite useful and valuable for studying transplant immunobiology. However, its technical complexity and high mortality have hindered widespread use. We sought to review and analyze the various techniques of kidney transplant in mice to prevent pitfalls and reduce complications. MATERIALS AND METHODS We searched PubMed using the key words "kidney t...

Epidemiologic and clinical characteristics of cytomegalovirus (CMV) infection and disease were analyzed retrospectively in 159 autologous marrow transplant recipients. The probability of CMV infection by day 100 after transplant was 22.5% in patients seronegative to CMV before transplant versus 61.1% in seropositive patients (P less than .0001 by logrank test). Multivariate analysis identified ...

Abstract Background and Aims Abruptly decreased kidney function is one of the common scenarios after heart transplantation risk factors for renal dysfunction in this population can be various. The purpose present study was to determine incidence predictors among 126 patients early postoperative period between January 2015 November 2019. Method conducted at department cardio-thoracic intensive c...

BACKGROUND Children undergoing heart transplant are at higher risk of developing post-transplant lymphoproliferative disorder (PTLD) than other solid organ recipients. The factors driving that unclear. This study investigated for PTLD in children transplanted 1 2 United Kingdom pediatric cardiac transplantation centers. METHODS All (<18 years, n = 200) our institution over a 16-year period were...

The objective was to evaluate the prognostic impact of pre-transplant minimal residual disease (MRD) as determined by real-time quantitative polymerase chain reaction in 67 adult NPM1-mutated acute myeloid leukemia patients receiving allogeneic hematopoietic stem cell transplantation (HSCT). Twenty-eight of the 67 patients had a FLT3-ITD (42%). Median age at transplantation was 54.7 years, medi...

BACKGROUND Acute kidney injury (AKI) is common in the kidney transplant population. OBJECTIVE To derive a multivariable survival model that predicts time to graft loss following AKI. DESIGN Retrospective cohort study using health care administrative and laboratory databases. SETTING Southwestern Ontario (1999-2013) and Ottawa, Ontario, Canada (1996-2013). PATIENTS We included first-time...

The aim of this study was to assess the magnitude of the survival benefit of renal transplantation compared with dialysis in patients selected for transplantation in Scotland. Longitudinal study of survival and mortality risk in all adult patients (1732) listed for a first transplant between January 1, 1989, and December 31, 1989, in Scotland. A time-dependent Cox regression analysis adjusted f...