BACKGROUND This study describes a new method for determining site-specific vascular shear stress using dynamic measures of shear rate and blood viscosity (BV) in the carotid arteries, and examines characteristics of carotid arterial shear stress among patients with lacunar infarction. METHODS Vascular shear stress measurements were conducted in 37 patients (17 lacunar infarction patients and ...

in this paper a laboratory study has been carried out on the effect of changing the type of soil filling cylindrical reinforcing elements from sm to gm on behavior of sandy soil. in this study the primary tests for evaluation of the impact of reinforced sand and gravel columns with diameters of 5 cm and heights of 15 cm subjected to vertical stresses of 50, 100, and 150 kpa were carried out in ...

A cumulative damage mechanism for short fiber type C/SiC during shear loading–unloading testing was examined and quantified using Iosipescu specimens parallel in the in-plane through-thickness plane, by modified fracture mechanics theory referring to measured characteristics (crack length, number angle). nonlinear stress–strain relation found both specimens. Decrease apparent modulus confirmed ...

Once plaques intrude into the lumen, the shear stress they are exposed to alters with hitherto unknown consequences for plaque composition. We investigated the relationship between shear stress and strain, a marker for plaque composition, in human coronary arteries. We imaged 31 plaques in coronary arteries with angiography and intravascular ultrasound. Computational fluid dynamics was used to ...

This paper assesses the dynamic nonlinear free-field soil response under bidirectional horizontal non-uniform excitation through a series of multi-point 1 g shaking table tests. The bed was enclosed in an innovative box supported by array three shake tables and subjected to uniform ground motions one two directions. unidirectional excitations, both non-uniform, were compared discussed terms acc...

Endothelial cells (ECs) sense shear stress and transduce blood flow information into functional responses that play important roles in vascular homeostasis and pathophysiology. A unique feature of shear-stress-sensing is the involvement of many different types of membrane-bound molecules, including receptors, ion channels and adhesion proteins, but the mechanisms remain unknown. Because cell me...

The basic building blocks of nano-structured hierarchical cellular materials are nano-sized wires or plates. Due to the effects of surface elasticity and the initial stress/strain, their bending, torsion, stretching and transverse shear rigidities are not only size-dependent, but also tunable and controllable over a large range. Based on the closed form results of the bending, torsion, stretchi...

In this article, the thermo-elastic behavior of a functionally graded simple blade subjected to the mechanical and thermal loadings is presented, applying a semi-analytical method and a variable thickness cantilever beam model. A specific temperature gradient is employed between the root and the edges of the beam. It is assumed that the mechanical and thermal properties are longitudinal directi...