Background: With leading morbidity among malignant tumors in otorhinolaryngology, Nasopharyngeal carcinoma (NPC) is one of the most frequent China. Objectives: This study aimed to help radiotherapy doctors recognize and segment nasopharyngeal organs at risk NPC make a plan. Methods: The authors used B-spline mutual information transform, register, fuse Chinese Visible Human images with voluntee...

BACKGROUND Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease, for which there is currently no safe and effective drug for therapy. In this study, we explored the effects of taurine, tea polyphenols (TPs), or a combination thereof, on NASH rats. METHODS Rats were divided into a normal group, a high-fat diet induced model group and a treatment group (...

BACKGROUND Newly diagnosed WHO grade II-III or any WHO grade recurrent meningioma exhibit an aggressive behavior and thus are considered as high- or intermediate risk tumors. Given the unsatisfactory rates of disease control and survival after primary or adjuvant radiation therapy, optimization of treatment strategies is needed. We investigated the potential of dose-painting intensity-modulated...

Experimental methods are commonly used for patient-specific IMRT delivery verification. There are a variety of IMRT QA techniques which have been proposed and clinically used with a common understanding that not one single method can detect all possible errors. The aim of this work was to compare the efficiency and effectiveness of independent dose calculation followed by machine log file analy...

INTRODUCTION: Stereotactic radiosurgery (SRS) is a specific form of radiation therapy used to treat tumors and other abnormalities in the brain. This technique uses a few highly focused X-rays beams usually delivered in a single high-dose. To maximize the radiation dose in the tumor, and to minimize the damage in collateral healthy areas, the treatment uses a frame-like device that keeps the he...

In this study, we evaluated the performance of a three-dimensional (3D) dose verification system, COMPASS version 3, which has a dedicated beam models and dose calculation engine. It was possible to reconstruct the 3D dose distributions in patient anatomy based on the measured fluence using the MatriXX 2D array. The COMPASS system was compared with Monte Carlo simulation (MC), glass rod dosimet...

This study compares Monte Carlo (MC) with conventional treatment planning system (TPS) calculations. The EGS4nrc MC code, BEAMnrc, was commissioned to simulate a Varian 21Ex Linac. The accuracy of the simulations, including points blocked by the jaws, was evaluated by comparing MC with ion chamber and MOSFET measurements. Eight mesothelioma IMRT cases were planned using Eclipse (pencil beam and...

Introduction: The use of electrons in the electron therapy to destroy tumoral tissue is dedicated significant contribution of different methods of radiation therapy. Scattered radiation due to exited electrons of the applicator affect the dose out of the field in the patient's normal tissue. The aim of this study is to determine the peripheral dose outside the applicator in the...

Radiochromic and radiographic films are widely used for radiation dosimetry due to the advantage of high spatial resolution and two-dimensional dose measurement. Different types of scanners, including various models of flatbed scanners, have been used as part of the dosimetry readout procedure. This paper focuses on the characterization of the EBT2 film response in combination with a Microtek S...

Background: One major challenge in brachytherapy is to verify the accuracy of dose distributions calculated by the treatment planning system. In this project, a new phantom design has been introduced for quality assurance of dose distributions in gynocological (GYN) brachytherapy implants using EBT GafChromic film. Materials and Methods: This phantom has been designed and fabricated from 90 sla...