detail_view&confID=40&abstractID=34492; cited May 8, 2008] 25. Hodgson D, Urbach D, Przybysz R, Gong Y, Sullivan T, Rabeneck L. Cancer surgery. Chapter 2. In: Tu JV, Pinfold SP, McColgan P, Laupacis A, eds. Access to Health Services in Ontario. Toronto: Institute for Clinical Evaluative Sciences; April 2005: 10. [Available online at: www.ices.on.ca/WebBuild/ site/ices-internet-upload/file_colle...

With the current practice of surveillance programs in high-risk patients, early stage hepatocellular carcinoma HCC is commonly diagnosed. This poses great challenge to clinicians, in terms of prognostic estimation, patient stratification to various treatment modalities and patient management during long-term follow-up. This review focuses on the current trends in the management of HCC, with spe...

BACKGROUND Sarcopenia, the age related decline in muscle mass, is associated with a reduction in muscle function, physical performance, quality of life, and loss of independence. Exercise, specifically resistance (weight) training, has been shown to be an effective countermeasure, arresting decline and substantially improving physical function. OBJECTIVE This article reviews the prevalence of...

OBJECTIVE The first aim was to integrate commonly used tinnitus measures into a comprehensive questionnaire. Second, the effectiveness of a masking therapy based on multiple-frequency matching was verified in a clinical study. This study investigated the feasibility of a new treatment strategy for tinnitus, with two main foci. MATERIALS AND METHODS Compare multiple-frequency matching with tra...

Malignant glioma, the most common human brain cancer, is almost uniformly fatal. Median survival is less than one year. The principal strategies of gene therapy for treatment of gliomas, including antisense approach, have been proposed comming from 1990s [1, 2, 3, 4]. The antisense oligonucleotides become the important tool of anti-cancer approach [5, 6]. The "discovery" of antisense approach w...

Hepatocellular carcinoma (HCC) has some unique characteristics in the digestive organ cancer. Therefore it is very important to select an appropriate treatment for recurrent HCC according to several situations such as the type of recurrence, previous treatments and conditions of patient. This article is a review of the concept of recurrent multiple HCC and its therapeutic strategies.

The main objectives of the current treatment of rheumatoid arthritis are disease control, inhibition of radiographic progression and finally remission. Presumptions to achieving these goals are early diagnosis of rheumatoid arthritis and early administered therapy with disease modifying drugs as monotherapy or combination of drugs. The optimal therapeutic response is influenced by tight control...

For the treatment of critical limb ischemia, collaboration with wound specialists and cardiologists performing revascularization is important. The foot care unit affiliated with related departments opened at our hospital in July 2010 for limb salvage, mainly under the leadership of the departments of cardiovascular internal medicineand plastic surgery. We have treated 194 patients up until Octo...

BACKGROUND The management of giant omphalocele (GO) presents a major challenge to pediatric surgeons. Current treatment modalities may result in wound infection, fascial separation, and abdominal domain loss. We report a GO infant who required a delayed closure and was managed using sterile incision drape and polypropylene mesh. METHODS A 3080 g full-term female infant was born with a GO. The...

this study intended to develop a model describing speaking strategies for efl learners by taking into account the effects of learners’ gender and proficiency on the application of strategies. accordingly, this study was planned to have two main analyses, namely qualitative and quantitative. in this respect, 30 efl learners' viewpoints were sought, and then, based on the elicited responses, a 21...