BACKGROUND Klinefelter's syndrome (KS) has been associated with tremor, but reports on tremor phenomenology and treatment are limited. CASE REPORTS Patient 1 is a 17-year-old male with a dystonic tremor treated with deep brain stimulation (DBS). Patient 2 is a 57-year-old male with a predominant left hand resting tremor and dystonic features. DISCUSSION Our cases suggest that the tremor in ...

This paper presents a two stage algorithm for real-time estimation of instantaneous tremor parameters from gyroscope recordings. Gyroscopes possess the advantage of providing directly joint rotational speed, overcoming the limitations of traditional tremor recording based on accelerometers. The proposed algorithm first extracts tremor patterns from raw angular data, and afterwards estimates its...

An algorithm to measure vocal tremor is presented, validated, and applied. The expected input is a sound file that captures a sustained phonation. The 6 output values are the frequency of frequency and amplitude tremor, intensity indices of frequency and amplitude tremor, and power indices of frequency and amplitude tremor. Basic principles of the algorithm are (1) autocorrelations of pitch and...

Vocal tremor is encountered in different neurological diseases and could be used for their characterisation. In this paper, vocal tremor features have been extracted for speakers with Parkinson’s disease and control speakers. It is shown that Parkinson’s disease has significant effects on vocal tremor features. For speakers with Parkinson’s disease, the average vocal frequency is higher and the...

Lamotrigine (LTG) is associated with a tremor when given in combination with valproic acid; however, a tremor associated with lamotrigine monotherapy is rare. Here, we report a case of positional and action tremor associated with lamotrigine use. Based on the temporal relationship, it is conceivable that lamotrigine increases serotonin transmission or affects basal ganglia dopamine activity, th...

This paper establishes a standard method for measuring human tremor. The electronic instrument described is an application of this method. It solves the need for an effective and simple tremor-measuring instrument fit for wide distribution. This instrument consists of a piezoelectric accelerometer connected to an electronic circuit and to an LCD display. The signal is also analysed by a compute...

Barcroft, Peterson, and Schwab (1952) and more recently Constas (1962) have shown that an intravenous infusion of adrenaline aggravates the tremor of patients with Parkinsonism. This observation raises two interesting questions. First, what are the effects on tremor of other drugs which act upon the autonomic nervous system? An answer to this question might throw some further light upon the pha...

INTRODUCTION Smart phones are becoming ubiquitous and their computing capabilities are ever increasing. Consequently, more attention is geared toward their potential use in research and medical settings. For instance, their built-in hardware can provide quantitative data for different movements. Therefore, the goal of the current study was to evaluate the capabilities of a standalone smart phon...

BACKGROUND Clinical characteristics reminiscent of cerebellar tremor occur in patients with advanced essential tremor. Ballistic movements are known to be abnormal in cerebellar disease. The hypothesis was proposed that ballistic movements are abnormal in essential tremor, reflecting cerebellar dysfunction. OBJECTIVE To elucidate the role of the cerebellum in the pathophysiology of essential ...

Rest tremor is one of the main symptoms in Parkinson's disease (PD), although in contrast to rigidity and akinesia, the severity of the tremor does not correlate well with the degree of dopamine deficiency or the progression of the disease. Studies suggest that akinesia in PD patients is related to abnormal increased beta (15-30 Hz) and decreased gamma (35-80 Hz) synchronous oscillatory activit...