Tandem carbenoid generation, ylide formation and [2,3]-rearrangement is a powerful method for the construction of bicyclic and linearly fused tricyclic systems containing a seven-membered ring.

The tricyclic core of lycoposerramine S has been synthesised in 10 steps from a symmetrical cyclohexadiene precursor by way of a desymmetrising free-radical cyclisation and iodocyclisation.

A set of complex tricyclic compounds containing several functional groups and multiple stereogenic centers has been prepared in only two steps with excellent diastereo- enantioselectivities. The synthesis takes advantage the highly versatile enantioselective Pd-catalyzed allylic substitution simple cyclic acetates or carbonates to form chiral 1,6-, 1,7- 1,8-enynes, which are then diastereoselec...

A novel structural interconversion unit based on intramolecular boroxine formation has been developed. The of a macrocyclic triboronic acid (blue Japanese umbrella) and tricyclic (green pinwheel) can be triggered by water or temperature. These unique interconversions are attributed to the entropic advantage formation. More information found in Research Article K. Ono co-workers (DOI: 10.1002/ch...

Palladium-catalyzed hydroarylations and additional domino reactions of aza-bicyclic and tricyclic norbornene derivatives were investigated and a series of new epibatidine analogues were synthesized.