Background: Both postprandial hyperglycaemia and hypertriglyceridaemia have been identified as risk markers for cardiovascular disease. However, the determinants of the magnitude of postprandial triglyceride and glucose responses are largely unknown. The objective was to assess potential determinants of postprandial glucose and triglyceride responses following two consecutive meals in women wit...

After intravenous injection of palmitate-1-(14)C to rats fed a choline-deficient (CD) or choline-supplemented (CS) diet for 15-18 hr, liver triglycerides became labeled very rapidly. In CS, but not in CD rats, there was a considerable loss, with time, of radioactivity from liver triglycerides. At the same time, significantly less radioactivity appeared in plasma triglycerides of CD rats than of...

Arachidonic acid was incorporated into triglycerides by cultured bovine endothelial cells in a time- and concentration-dependent manner. At 75 microM or higher, more arachidonic acid was incorporated into triglycerides than into phospholipids. The triglyceride content of the cells increased as much as 5.5-fold, cytoplasmic inclusions appeared, and arachidonic acid comprised 22% of the triglycer...

Obesity is associated with leptin resistance as evidenced by hyperleptinemia. Resistance arises from impaired leptin transport across the blood-brain barrier (BBB), defects in leptin receptor signaling, and blockades in downstream neuronal circuitries. The mediator of this resistance is unknown. Here, we show that milk, for which fats are 98% triglycerides, immediately inhibited leptin transpor...

Specific activities and total radioactivity of liver and serum triglycerides were determined, in glucose-fed rats, at various times after a single intravenous injection of palmitatel-CI4. A multicompartmental model of plasma and liver triglyceride metabolism was constructed which was compatible with the known physiological and biochemical behavior of triglycerides and the observed data. The rat...

BACKGROUND Microalgal triglycerides (TAGs) hold great promise as sustainable feedstock for commodity industries. However, to determine research priorities and support business decisions, solid techno-economic studies are essential. Here, we present a techno-economic analysis of two-step TAG production (growth reactors are operated in continuous mode such that multiple batch-operated stress reac...

We describe a single-reagent, enzymatic procedure for triglycerides in serum, which may be performed in 5 min per sample with use of an Abbott ABA-100 analyzer system. This procedure is compared to the semi-automated enzymatic procedure with the ABA-100, which requires 30 min per sample.

Despite the extensive literature on the relationship of lipid and lipoprotein particles to coronary heart disease (CHD) incidence, the specific association of triglycerides with incident CHD has arguably generated more disagreement than any other measure. The most parsimonious explanations for this controversy are that contradictory results abound and that positive studies typically show a mode...

Michael Miller, MD, FAHA, Chair; Neil J. Stone, MD, FAHA, Vice Chair; Christie Ballantyne, MD, FAHA; Vera Bittner, MD, FAHA; Michael H. Criqui, MD, MPH, FAHA; Henry N. Ginsberg, MD, FAHA; Anne Carol Goldberg, MD, FAHA; William James Howard, MD; Marc S. Jacobson, MD, FAHA; Penny M. Kris-Etherton, PhD, RD, FAHA; Terry A. Lennie, PhD, RN, FAHA; Moshe Levi, MD, FAHA; Theodore Mazzone, MD, FAHA; Sub...

A new method for the stereospecific analysis of triglycerides is demonstrated on a corn oil which had been analyzed by an earlier method. The triglyceride (1,2,3-triacyl L-glycerol) was partially degraded by means of methyl magnesium bromide. The 1,3-diglyceride was then isolated, and converted into l-2-phosphatidyl phenol, from which phospholipase A cleaved the fatty acids from position 1. The...