In this paper, novel liver-targeting nanoparticles (NPs), lactosyl-norcantharidin (Lac-NCTD)-associated N-trimethyl chitosan (TMC) NPs (Lac-NCTD-TMC-NPs), were prepared using ionic cross-linkage. The physical properties, particle size, and encapsulation efficiency of the nanoparticles were then investigated. The continuous line of heterogeneous human epithelial colorectal adenocarcinoma cells (...

BACKGROUND The aim of this study was to evaluate the clinical and radiological outcomes of the use of a new 3D-printed anatomy-adaptive titanium mesh cage (AA-TMC) for single-level anterior cervical corpectomy and fusion (ACCF) in patients with cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL). MATERIAL AND METHODS We retrospectively reviewed t...

The column density of the OH radical in Taurus Molecular Cloud-1 (TMC-1), reaches its maximum close to the cyanopolyyne peak. A comparison with previously published maps of other molecules shows that OH has a similar distribution as HC3N and CCS, but differs largely from CS, SO, NH3 and N2H. The OH/C18O column density ratio is, however, almost constant along the dense ridge of TMC-1, suggesting...

Among the current biomaterial applications, the use of biopolymers as cell scaffolds could aid the development of stem cell-based therapies aimed at replacing tissue loss due to injuries or diseases, such as during myocardial infarction. Embryonic stem cells (ESC) provide a great therapeutic potential for cardiac tissue. In this study, the interaction of mouse embryonic stem cells (mESC) with p...

The presence of an 'underfill' encapsulant between a micro-electronic device and the underlying substrate is known to substantially improve the thermal fatigue life of flip-chip solder joints, primarily due to load-transfer from the solder to the encapsulant. In this study, a new single joint-shear (SJS) test, which allows the measurement of the strain response of an individual solder ball duri...

The effect of configuration of an asymmetric bulky initiator 2,2’-[1,1’-binaphtyl-2,2’-diyl10 bis-(nitrylomethilidyne)]diphenoxy aluminum isopropoxide (Ini) on structure of copolymer of 11 asymmetric monomer L,L-lactide (Lac) with symmetric comonomer trimethylene carbonate (Tmc) 12 was studied using polarimetry, dilatometry, SEC and 13C NMR. When the S-enantiomer of Ini was 13 used the distribu...

A positive effect of intra-articular platelet-rich plasma (PRP) injection has been discussed for osteoarthritic joint conditions in the last years. The purpose of this study was to evaluate PRP injection into the trapeziometacarpal (TMC) joint. We report about ten patients with TMC joint osteoarthritis (OA) that were treatedwith 2 intra-articular PRP injections 4weeks apart. PRPwas produced usi...

A novel thin-film composite (TFC) reverse osmosis (RO) membrane was developed by the interfacial polymerization (IP) of trimesoyl chloride (TMC) and m-phenylene diamine (MPD) on the hollow fibre ultrafiltration polysulphone (PS) membrane. The performance of the TFC membrane was optimized by studying the preparation parameters, which included monomer TMC concentration, monomer MPD concentration ...

TWO constituencies form the backbone of a journal and act as stewards of its quality. One is the Editorial Board, whose judgments on the quality of manuscripts shape a journal signifi cantly and set the tone for its direction. Equally important, but perhaps not as externally visible, is the body of external reviewers who are called upon to review manuscripts. The IEEE Transactions on Mobile Com...

BACKGROUND The production of protein drugs has recently increased due to advances in biotechnology, but their clinical use is generally limited to parenteral administration due to low absorption in non-parenteral administration. Therefore, non-parenteral delivery systems allowing sufficient absorption draw much attention. METHODS Microparticles (MP) were prepared using chitosan-4-thio-butylam...