Purpose This is a case report of an unusual case of the family transmission of Streptococcus pyogenes infection in three siblings. One brother contracted the infection which resulted in orbital cellulitis of two of his siblings, in the absence of anatomical or immunological predisposing factors. Observations A young boy contracted an uncomplicated S pyogenes upper respiratory tract infection....

Streptococcus pyogenes is a leading cause of pharyngeal infection, with an estimated 616 million cases per year. The human nasopharynx represents the major reservoir for all S. pyogenes infection, including severe invasive disease. To investigate bacterial and host factors that influence S. pyogenes infection, we have devised an improved murine model of nasopharyngeal colonization, with an opti...

BACKGROUND Impetigo is caused by both Streptococcus pyogenes and Staphylococcus aureus; the relative contributions of each have been reported to fluctuate with time and region. While S. aureus is reportedly on the increase in most industrialised settings, S. pyogenes is still thought to drive impetigo in endemic, tropical regions. However, few studies have utilised high quality microbiological ...

Streptococcus pyogenes is a clinically important pathogen consisting of various serotypes determined by different M proteins expressed on the cell surface. The M type is therefore a useful marker to monitor the spread of invasive S. pyogenes in a population. Serotyping and nucleic acid amplification/sequencing methods for the identification of M types are laborious, inconsistent, and usually co...

Streptococcus pyogenes is a significant bacterial pathogen in humans. In this study, histidine-rich glycoprotein (HRG), an abundant plasma protein, was found to kill S pyogenes. Furthermore, S pyogenes grew more efficiently in HRG-deficient plasma, and clots formed in this plasma were significantly less effective at bacterial entrapment and killing. HRG-deficient mice were strikingly more susce...

The aim of this study was to determine the percentage of participation of particular species of microorganisms, isolated from the uterus of cows with endometritis and from cows without inflammatory lesions of the uterus, in the same postpartum period. The aim of the study was also to examine how long after parturition non-treated endometritis persists. Moreover, antibiotic susceptibility tests ...

Streptococcus pyogenes is the major bacterial pathogen responsible for acute pharyngitis in children. Oral penicillin is the drug of choice for streptococcal pharyngitis, while macrolides are an alternative option for patients allergic to penicillin. The frequent use of macrolides promotes the spread of erythromycin resistance (1-2), but reducing the use of these antibiotics has been correlated...

  Abstract   Background: The interest in using bacteria as anti- cancer therapeutic agents dates back to the end of the19th century. Some bacteria like Salmonella and Listeria replicate effectively inside malignant cell lines and suppress their growth. The bacterium Streptococcus pyogenes has become medically famous as a flesh-eating pathogen since mid-1980s. It is the causative agent of a life...

The diethyl ether and ethyl acetate fractions of the peel fruit Solanum incanum. (S. incanum) were analyzed using gas chromatography-mass spectrometry (GC–MS). 105 compounds identified in fraction 75 fraction. Among them, 5 by fragmentation pattern, discussed, compared with NIST database. antibacterial screening was also conducted for bothdiethyl S.incanum four pathogens, two Gram-positive bact...

In 82% of cows, contamination the genitals with conditionally pathogenic microflora E. coli was established in 17% cases, S. aureus - 15%, P. mirabilis 14%, pyogenes pyogenes, R. vulgaris, C. albicans 14.0%; aureus, coli, mirabilis, albicans, A. fumigatus, M. racemosus 12% cases latent endometritis. salpingitis, microorgans were isolated association 28.5% cases; 27.7% fumigatus 25.2%; 13.1%, re...