calcifying fibrous tumor (cft) is a rare mesenchymal tumor, affecting children and young adults with a predilection for the soft tissue and the abdominal cavity. cft of the tubular gastrointestinal tract is very rare with less than 20 cases of gastric cfts reported in english literature. this benign hypocellular fibrosclerotic calcifying lesion can resemble other spindle cell tumors particularl...

purpose : to review periocular dermoid cysts to determine distribution of demographic factors, and tumor location methods : in this retrospective, observational case series in a tertiary-care hospital, we reviewed all cases of histopathologically verified periocular dermoid cysts at our institution between 2003 and 2011. the study endpoints included: age, gender, and tumor location. results : t...

OBJECTIVE The objective of this study was to investigate 1) whether social housing condition, tumor size, and tumor growth rate alter responses to chemotherapy and 2) whether the timing of tumor cell injection or chemotherapy initiation (relative to housing condition formation) influences tumor growth rate or the efficacy of chemotherapy. METHODS Mice were reared individually (I) or in groups...

Microtentacles are mostly microtubule-based cell protrusions that are formed by detached tumor cells. Here, we report that the formation of tumor cell microtentacles depends on the presence and dynamics of guanine nucleotide-binding proteins of the septin family, which are part of the cytoskeleton. In matrix-attached breast, lung, prostate and pancreas cancer cells, septins are associated with ...

Abstract Inferior vena cava leiomyosarcoma (IVCL) is a rare malignant mesenchymal tumor. Surgical treatment challenge because it must combine free surgical margins with vascular reconstruction, using prosthetic or autologous grafts, primary suture, simple ligation without vein reconstruction. The option possible thanks to the slow growth of tumor, allowing collateral venous circulation develop....

The indictment of fat as a dietary constituent that potentiates carcinogenesis arose from a study of Watson and Mellanby in 1930 [1]. Animal diets containing high levels of butterfat (12.5-25%) were shown to enhance coal tar-induced skin tumor formation. After this seminal observation, intense investigations of the effects of dietary fat on chemically-induced carcinogenesis were conducted durin...

ameloblastomas are regarded as a homogeneous group of neoplasms with locally invasive character. they generally do not show induction of dental hard tissue formation except in few cases. biological behavior and histogenesis of these tumors is still unexplored as there is lack of relevant studies and long follow-up of these patients. so, we aimed to report this rare case of dentinoameloblastoma ...

Tumor-secreted extracellular vesicles (EVs) are the main mediators of cell-cell communication, permitting cells to exchange proteins, lipids, and metabolites in varying physiological pathological conditions. They contain signature tumor-derived molecules that reflect intracellular status their cell origin. Recent studies have shown tumor cell-derived EVs can aid cancer metastasis through modula...