zataria multiflora (zm) is a thyme-like aromatic plant in the lamiaceae family that grows in central and southern iran. zm is extensively used as a flavor ingredient in a wide variety of foods and is used as part of popular traditional folk remedies. in the present study, zm essential oil (zmo) was obtained from zm leaves via hydro-distillation and then analyzed by gc-ms (gas chromatography-mas...

background host genetic and environmental factors are involved in development of gastric cancer. tumor necrosis factor (tnf)-î±| has a key role in helicobacter pylori -induced gastritis. we analyzed the association between tnf-î± polymorphism and the risk of gastric cancer in an iranian population residing in northeastern iran. materials and methods in a case-control study, the genotyping was c...

conclusions traf6 plays an important role in the onset of colon cancer; therefore, drugs targeting it may have great clinical significance in the treatment of this disease. results the positive expression rate of traf6 in tumor tissues was 66.7%, which was significantly higher than in normal paracancerous tissues (18.5%). the positive expression rate of traf6 was significantly correlated with d...

the aim of this study was to examine the anti-inflammatory effects of co-administration of growthhormone-releasing peptide-2 (ghrp-2) and growth hormone (gh) on tumor necrosis factor-α (tnf-α),interleukin-6 (il-6) and inducible nitric oxide synthase (inos) gene expression induced by lps in the mousebrain. thirty-five male nmri mice (25±5 g) were injected through the mouse tail vein with saline,...

1. Cardiopulmonary bypass is associated with an increase in nitric oxide concentrations, and plasma levels of tumour necrosis factor and interleukin-1. Aprotinin, a serine protease inhibitor, commonly used during cardiopulmonary bypass to reduce blood loss, has been demonstrated to exhibit significant anti-inflammatory effects during and after cardiopulmonary bypass. 2. Airway nitric oxide was ...