نتایج جستجو برای: tumour targeting
تعداد نتایج: 205504 فیلتر نتایج به سال:
Objective The mechanisms underlying the contribution of primary tumour to pre-metastatic niche formation remains largely unknown in hepatocellular carcinoma (HCC). We previously reported that released LOXL2 from HCC cells under higher stiffness stimulation facilitated lung niche. Here, we further clarified pathological role promoting and metastasis occurrence its relevant molecular mechanism. M...
PV1 is an endothelial-specific protein with structural roles in the formation of diaphragms in endothelial cells of normal vessels. PV1 is also highly expressed on endothelial cells of many solid tumours. On the basis of in vitro data, PV1 is thought to actively participate in angiogenesis. To test whether or not PV1 has a function in tumour angiogenesis and in tumour growth in vivo, we have tr...
BACKGROUND The anti-idiotypic monoclonal antibody 105AD7 mimics the tumour associated antigen 791Tgp72, expressed on 70-80% of colorectal cancers. Phase I studies have shown that the vaccine is non-toxic, and a number of patients have been immunised prior to resection of their primary tumours. AIMS To assess lymphocyte activation at the tumour site by measuring expression of the alpha subunit...
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