Amphotericin B (AmB)/poly(lactic acid)-b-poly(ethylene glycol) (PLA-b-PEG) nanoparticles coated with polysorbate 80 (Tween-80) were prepared by nanoprecipitation for transport across the blood-brain barrier (BBB). The effects of Tween-80 on the size and distribution, entrapment efficiency and release behavior of AmB/PLA-b-PEG nanoparticles were investigated. Furthermore, the brain targeting and...

Tomat merupakan buah yang mengandung kadar air cukup tinggi dapat menyebabkan proses pembusukan. Menjadikan tomat ke bentuk bubuk melalui pengeringan adalah salah satu cara untuk mengawetkan tomat. Penelitian ini bertujuan mengetahui karakteristik serta pengaruh foaming agent tween 80 pada dengan variasi laju udara fan, waktu dan temperatur. Metode digunakan metode tray dryer. menggunakan varia...

OBJECTIVES In situ formation of nanocrystals and dissolution profiles of fenofibrate (FFB) from a self-microemulsifying drug delivery system (SMEDDS) were characterized. METHODS SMEDDS formulated with Myritol and surfactant mixture (Smix) of D-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS) and either Tween 20 (A, C, E, G, M, S, N, T, O) or Tween 80 (B, D, F, H, P, U, Q, V, R) at vario...

Toxicity by oral route administration of S. anacardium extract with peanut oil was compared against the same extract emulsified with Tween-80 saline. The traditional way of administration with peanut oil was found to be safe and upto 25 mg/kg/day x9 days, increase in weight, RBCs & haemoglobin % was observed without mortality. Same dose with Tween-80 saline was found to have adverse effects reg...

To degrade chrysene, a polycyclic aromatic hydrocarbon (PAH) found in crude oil contaminated soil by bioremediation the Polyporus sp. S133, a fungus collected from soil was used. Maximal degradation (86%) was obtained when Polyporus sp. S133 was incubated in 0.5% tween 80 for 30 days, as compared to 30% degradation rate without tween 80. Chrysene was indeed degraded by Polyporus sp. S133 throug...