As rock bursts are unavoidable in deep mines and excavations with high in-situ stresses, ground support systems implemented to manage mitigate bursts. Cable bolts commonly used as reinforcing elements systems, which subject dynamic loads burst-prone excavations. To design an efficient cable bolt conditions, shear energy absorption capacity must be considered. Numerical modelling is advantageous...

Noise produced by blast waves can be a problem, especially when an explosion occurs near populated areas. As one means of reducing the blast noise, the explosive is detonated in a pit, a space closed at the bottom and sides, open at the top. A two-dimentional finite difference model was used to simulate such an explosion in a pit and to determine to what extent the blast wave was attenuated. Th...

TRPA1 is a calcium ion channel protein recently identified as the infrared receptor in pit organ-containing snakes. Therefore, understanding the molecular evolution of TRPA1 may help to illuminate the origin of "heat vision" in snakes and reveal the molecular mechanism of infrared sensitivity for TRPA1. To this end, we sequenced the infrared sensory gene TRPA1 in 24 snake species, representing ...

The Pavlovian-to-instrumental transfer (PIT) paradigm probes the influence of Pavlovian cues over instrumentally learned behavior. The paradigm has been used extensively to probe basic cognitive and motivational processes in studies of animal learning. More recently, PIT and its underlying neural basis have been extended to investigations in humans. These initial neuroimaging studies of PIT hav...

PiT-1 and PiT-2 are related multiple transmembrane proteins which function as sodium-dependent phosphate transporters and as the cell receptors of several oncoretroviruses. Two copies of a homology domain that is found in distantly related species assign these proteins to a large family of phosphate transporters. A current membrane topology model of PiT-1 and PiT-2 predicts 10 transmembrane dom...

BACKGROUND The POU class 1 homeobox 1 transcription factor (POU1F1, also known as Pit-1) was reported to be associated with tumor progression and metastasis. The purpose of this study was to evaluate the prognostic value of Pit-1 in breast cancer patients. MATERIAL AND METHODS The relative expression levels of Pit-1 in breast cancer patients were detected by quantitative real-time PCR (qRT-PC...