Centromeres are specialized chromosome domains that control chromosome segregation during mitosis, but little is known about the mechanisms underlying the maintenance of their integrity. Centromeric ultrafine anaphase bridges are physiological DNA structures thought to contain unresolved DNA catenations between the centromeres separating during anaphase. BLM and PICH helicases colocalize at the...

the effect of pre-existing nano sized precipitates on the mechanisms and rate of grain refinement has been investigated during the severe plastic deformation. a binary al–0.2sc alloy, containing coherent al3sc particles, of 3.62 nm in diameter has been deformed by accumulative roll bonding up to 10 cycles. the resulting deformed structures were quantitatively analyzed using electron backscatter...

A combination of experimental and numerical approaches was applied for constructing a dynamic model thermomechanical processing, which used simulating laboratory rolling cooling, designing cooling path to enable phase transformation from austenite ultrafine ( ∼ 50–100 nm) bainitic laths. Physical simulation experiments were calibrating the models. Hot water conducted they numerically simulated....

BACKGROUND Occupational exposures to ultrafine particles in the plume generated during laser hair removal procedures, the most commonly performed light based cosmetic procedure, have not been thoroughly characterized. Acute and chronic exposures to ambient ultrafine particles have been associated with a number of negative respiratory and cardiovascular health effects. Thus, the aim of this stud...

We investigated whether slowed clearance after exposure to ultrafine particles was due to a failure in alveolar macrophage phagocytosis. This was achieved by measuring the ability of a macrophage cell line (J774.2 MPhi) to phagocytose 2-microg indicator latex beads following 8-h exposures to a number of test particles. Particles utilized were fine titanium dioxide (TiO2), ultrafine titanium dio...

in this study, the effects cold rolling and annealing parameters during thermomechanical processing of the aisi 201ln stainless steel were investigated. the cast samples were homogenized, hot-rolled and solution-annealed to acquire a suitable microstructure for the subsequent thermomechanical treatment. unidirectional and transverse multi-pass cold rolling at 25, 0 and -15 °c was carried out to...

in this study, ultrafine grained 2024 al alloy based b4c particles reinforced composite was produced by mechanical milling and hot extrusion. mechanical milling was used to synthesize the nanostructured al2024 in attrition mill under argon atmosphere up to 50h. a similar process was used to produce al2024-5%wt. b4c composite powder. to produce trimodal composites, milled powders were combined w...

accumulative roll-bonding (arb) is a severe plastic deformation process that is using rolling to produce ultrafine grains in coarse grained metallic materials. in this study, arb has been applied on 70/30 brass up to 6 cycles at ambient temperature and non-lubricated conditions to apply a true strain up to 4.8 von mises strain. microstructures of arbed brass samples were characterized by scanni...

Effects of the filament diameter on the microstructure and the critical current density (J ) were investigated in the external diffusion processed multififamentary Nb Sn-Cu superconducting composites. J was measured in transvere magnetic fields(H) of 10-17 Tesla. The mi~rostructures were examined using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) after each step...

Aluminum-doped zinc oxide (AZO) films have been synthesized using reactive high power impulse magnetron sputtering (HiPIMS) in a wide range of Al contents, 0.6–14.7 at.%. The film structure and microstructure investigated by X-ray diffraction transmission electron microscopy evolves from nanocrystalline columnar towards ultrafine wurtzite ZnO upon increasing the content. Electrical properties m...