Gross and ultrastructural changes occurring in the left ventricle in response to chronic volume overload were studied in dogs. One group of dogs was examined 28-43 days after an aortocaval fistula had been created; congestive heart failure had developed at the time of the examination. Two other groups of dogs were investigated 78 ± 17 (SD) days and 178 ± 4 days after similar fistulas had been c...

Gross and ultrastructural changes occurring in the left ventricle in response to chronic volume overload were studied in dogs. One group of dogs was examined 28-43 days after an aortocaval fistula had been created; congestive heart failure had developed at the time of the examination. Two other groups of dogs were investigated 78 ± 17 (SD) days and 178 ± 4 days after similar fistulas had been c...

Soon after denervation, skeletal muscle undergoes ultrastructural and molecular changes that ultimately lead to muscle atrophy and cell death. Functional electrical stimulation (FES) is effective in preventing the atrophy of denervated muscles, but it is unclear whether FES can prevent the progression of ultrastructural changes in the sarcotubular system and cell death after denervation. In thi...

background and objective: evaluation of degenerative changes of motoneurons and their related synapses can be useful in understanding the mechanisms of neurodegenerative diseases and their potential treatment. the present electron microscopic and immunohistochemical study investigates the axotomy-induced changes of adult spinal motoneurons up to 3 months following sciatic nerve transection. mat...

OBJECTIVES The goal of this study was to investigate the effects of ischemia-reperfusion on myocardial ultrastructure in patients with and without hibernating myocardium. BACKGROUND It is generally accepted that chronically dysfunctional, hibernating myocardium may remain nonetheless viable for a long time. It has been postulated that hibernating myocytes may survive, despite being subtended ...