The deformational behavior of articular cartilage has been investigated in confined and unconfined compression experiments and indentation tests, but to date there exist no reliable data on the in situ deformation of the cartilage during static loading. The objective of the current study was to perform a systematic study into cartilage compression of intact human femoro-patellar joints under sh...

In this study, we investigated the depth-dependent metabolic and structural responses of adult articular cartilage to large-strain, static, unconfined compression. Changes in cell biosynthetic activity and several morphometry-based structural parameters (cell density, cell volume fraction, cell surface-area density, mean cell surface area, and mean cell volume) were measured at eight sites repr...

OBJECTIVE To study mechanical overload of mature meniscal tissue under normal and pro-inflammatory conditions in vitro. METHOD Three days after a single unconfined compression (strain: 25-75%, strain rate 1/s) of meniscal explants from 16 to 24 months-old cattle combined with interleukin-1-treatment (IL-1, 10 ng/ml) release of glycosaminoglycans (GAGs; dimethylmethylene blue (DMMB) assay), la...

The study focuses on the synthesis of a novel polymeric scaffold having good porosity and mechanical characteristics synthesized by using natural polymers and their optimization for application in cartilage tissue engineering. The scaffolds were synthesized via cryogelation technology using an optimized ratio of the polymer solutions (chitosan, agarose and gelatin) and cross-linker followed by ...

This study investigates the strength enhancement of Tin Slag Polymer Concrete (TSPC) under hybrid GFRP and CFRP confinement in comparison with mono on TSPC circular short column samples. Hybrid FRP is prepared by wrapping followed both 1 layer using epoxy Sikadur 330 as matrix binders 50 mm overlap. Compression test was performed unconfined (TSPC-UC), (TSPC-GF), (TSPC-CF) (TSPC-HB) 1mm/ min loa...

The paper presents experimental results from unconfined compression and splitting tensile tests used in combination order to estimate the cohesion intercept of unsaturated soils. Samples different soils form slurry were subjected various suction values using axis translation technique a pressure plate extractor then these samples removed tests. Mohr’ circles for two loading conditions drawn tan...