Career adaptability is a psychosocial resource that aids in coping with current and anticipated tasks, transitions, traumas people experience their occupational roles. Although there great deal of evidence career relates to important outcomes, the role it perceived play involuntary, radical, socially undesirable changes understudied. Grounded construction theory, we conducted study an experimen...

Cancer multidrug resistance (MDR) is one of the main mechanisms contributing to therapy failure and mortality. Overexpression drug transporters ABC family (ATP-binding cassette) a major cause MDR. Extracellular vesicles (EVs) are nanoparticles released by most cells organism involved in cell–cell communication. Their cargo mainly comprises, proteins, nucleic acids, lipids, which transferred fro...

We explore a new general-purpose heuristic for finding high-quality solutions to hard discrete optimization problems. The method, called extremal optimization, is inspired by self-organized criticality, a concept introduced to describe emergent complexity in physical systems. Extremal optimization successively updates extremely undesirable variables of a single suboptimal solution, assigning th...

We explore a new general-purpose heuristic for finding high-quality solutions to hard discrete optimization problems. The method, called extremal optimization, is inspired by self-organized criticality, a concept introduced to describe emergent complexity in physical systems. Extremal optimization successively updates extremely undesirable variables of a single suboptimal solution, assigning th...

Many industries such as paper, food, cosmetics, textiles etc. use dye in order to colour their products. The presence of these dyes in water even at very low concentration is highly visible and undesirable. Colour is the first contaminant to be recognised. Photocatalytic technique and adsorption methods offer a good potential to remove colour from wastewater. In the present paper these two meth...

The ability to automatically compose Web Services is critical for realising more complex functionalities. Several proposals to use automated planning to deal with the problem of service composition have been recently made. We present an approach, based on modelling the problem as a CSP (Constraint Satisfaction Problem), that accommodates for the use of numeric variables, sensing and incomplete ...

A qualitative probabilistic network is a graphical model of the probabilistic influences among a set of statistical variables in which each influence is associated with a qualitative sign. A non-monotonic influence between two variables is associated with the ambiguous sign ’?’, which indicates that the actual sign of the influence depends on the state of the network. The presence of such ambig...

The well known ”beauty defect” of probabilistic neural networks is the biologically unnatural complete interconnection of neurons with all input variables. Despite of deep formal reasons of this undesirable property, it can be removed by a special subspace approach without leaving the exact framework of Bayesian decision-making. As shown in a recent paper the related structural optimization bas...