Venous thromboembolism in pregnancy is a clinical emergency that has been associated with significant risk for maternal and fetal morbidity and mortality. The adaptation of the maternal hemostatic system to pregnancy predisposes women to an increased risk of thromboembolism. A timely diagnosis of deep venous thrombosis is crucial because up to 24% of patients with untreated deep venous thrombos...

Hyperthyroidism and thyrotoxicosis are hypermetabolic conditions that cause significant morbidity and mortality. The diagnosis can be difficult because symptoms can mimic many other disease states leading to inaccurate or untimely diagnoses and management. Thyroid storm is the most severe form of thyrotoxicosis, hallmarked by altered sensorium, and, if untreated, is associated with significant ...

Sleep apnoea is a common condition in the elderly population with potentially significant consequences, including comorbidity and cognitive decline. There now wealth of information indicating that untreated sleep apnea associated an increased risk fatal nonfatal cardiovascular event, higher propensity sudden death during greater for stroke all-cause mortality. Consequently, OSA represents evolv...

The delivery of healthcare to patients with chronic non-communicable diseases has been challenging during the COVID-19 pandemic. Cardiovascular constitute leading causes morbidity and mortality in western world beyond. Telecardiology services are essential for continuity medical care, prevention,and early diagnosis disease exacerbations. This is a dire need both patients, who can experience lon...

Atrial fibrillation (AF) is the most common cardiovascular disorder present in as many as 9% of subjects aged ≥65 years and costing the United States >26 billion dollars a year. It causes significant morbidity and mortality with 750 000 hospitalizations each year and contributing to an estimated 130 000 deaths each year. Risk factors for AF such as obesity, diabetes mellitus, coronary artery di...

Isolated tubal torsion is a rare event. The clinical presentation is often nonspecific and the diagnosis is difficult, especially in the gravida abdomen. If left untreated, torsion can result in premature labour and foetal loss, as well as maternal morbidity. Here we present a case of isolated tubal torsion in a primigravida occurring in her third trimester and subsequent successful laparoscopi...

Articular cartilage injuries remain a clinical challenge and are known to double the incidence of degenerative joint disorders if left untreated. Current therapeutic options suffer from major drawbacks, such as defect-size limitations, long and complex rehabilitation times, donor-site morbidity and limited graft material. Even the more advanced cell-based therapies show highly variable clinical...

Drug-addiction may trigger early onset of age-related disease, due to drug-induced multi-system toxicity and perilous lifestyle, which remains mostly undetected and untreated. We present the literature on pathophysiological processes that may hasten aging and its relevance to addiction, including: oxidative stress and cellular aging, inflammation in periphery and brain, decline in brain volume ...

Parents of morbidly obese children face a Hobson’s choice between losing custody of their child for medical neglect and subjecting their child to a regimen of increasingly dangerous interventions to control the child’s weight. The incidence of pediatric obesity has risen in recent years and presents serious lifelong risks to the child if left untreated. Roux-en-Y gastric bypass is the only medi...

The risk of protein calorie malnutrition among the community dwelling elderly is high. If undetected or untreated malnutrition can raise risks of morbidity and mortality. Therefore, improving screening, assessment and treatment of malnutrition, particularly in ambulatory settings that serve the elderly is imperative. The aim of this paper is to briefly detail the diagnostic criteria for protein...