QUESTION Some of my pregnant patients complain about pruritus. Are there conditions in pregnancy that present with pruritus that might put the mother or fetus at risk? ANSWER Although most cases of pruritus can be attributed to itchy dry skin, there are conditions unique to pregnancy that involve pruritus as a leading symptom. These include pemphigoid gestationis, pruritic urticarial papules ...

Brachioradial pruritus is characterized by the presence of pruritus on the lateral aspect of the arms. The etiology of this enigmatic entity is the subject of some debate some authors claim that brachioradial pruritus is a photodermatosis whereas others attribute it to the presence of underlying cervical radiculopathy. In these case reports, we present our experience with brachioradial pruritus...

Most pruritus occurs in association with skin diseases; but gingival pruritus seldom seen in associated with oral dysesthesia. Most clinicians, including dental practitioners, do not know about how to deal with gingival pruritus. Our patient was a 74-year-old Japanese female who attended the Department of Oral Medicine, Tokushima University Hospital, because of gingival pruritus. Pregabalin was...

Objective: The aim of this meta-analysis is to evaluate the effect of ondansetron in the prevention of pruritus after use of intrathecal fentanyl. Methods: The main outcomes were the relative risks (RR) and the 95% confidence intervals (CI) regarding the incidence of pruritus and other side effects. Results: Ten trials totaling 1,084 patients were analyzed. Subgroups results suggested that ther...

Chronic pruritus, one of the main symptoms in dermatology, is often intractable and has a high impact on patient's quality of life. Beyond dermatologic disorders, chronic pruritus is associated with systemic, neurologic as well as psychologic diseases. The pathogenesis of acute and chronic (>6 weeks duration) pruritus is complex and involves in the skin a network of resident (e.g., sensory neur...

Chronic pruritus is frequently refractory to currently available treatments. Studies suggest that pruritus may arise from an imbalance of the mu- and kappa-opioid receptor system activity in either the skin or the central nervous system. Stimulation of kappa-opioid receptors by their agonists inhibits pruritus in both animals and humans. The antipruritic effect of kappa-opioid receptors agonist...

INTRODUCTION Cholestasis related pruritus, secondary to intrahepatic and/or extrahepatic biliary obstruction is a common manifestation in chronic liver disease. Pruritus is difficult to treat, and results are often suboptimal. A stepwise medical approach is usually employed, followed by a trial molecular adsorbents recirculation system in medication resistant cases. Pruritus resulting in reduce...

New insights in uremic toxins. The retention in the body of The retention compounds, which are considered recompounds, which normally are secreted into the urine results sponsible for the uremic syndrome, are uremic toxins. in a clinical picture, called the uremic syndrome. The retention Before a retention solute can be accepted as a true urecompounds responsible for the uremic syndrome are cal...

background and objective: hemolytic uremic syndrome (hus) is the most prevalent cause of children renal insufficiency which in many cases (90%) occurs following diarrhea. hemolytic microangiopathic anemia, thrombocytopenia, and renal insufficiency are main symptoms of hemolytic uremic syndrome. this study aims to consider the relationship between pathologic data of nephro-biopsy and laboratory ...